background: the outcomes of such pregnancies have been rarely evaluated in our country. a descriptive study was planned to assess the health and condition of neonates conceived with assisted techniques in a one year period. materials and methods: at royan institute, tehran, 443 women who became pregnant by one of the assisted techniques in vitro fertilization (ivf), intrauterine insemination (i...

background: infections are one of the correctable causes of infertility with low cost and cost effective treatment. the 50% of infertile cases is related to men in some way, and 30% of them are absolutely related to them. mycoplasmas are the smallest microorganisms with capability of dna replication. present study is planned to compare the mycoplasma infection in infertile men and men with esta...

introduction: the morphology and ultrastructure of germinal epithelum basement memberane (bm) in patients with non-obstructive azoospermia was studied by means of transmision electron microscipy. materials and methods: 10 biopsies of testis tissue from patients with non-obstructive azoospermia referred to royan institute as patients group and 5 biopsies from patients with prostatic cancer as co...

background: uterine rupture at the site of a previous cesarean scar is an uncommon but catastrophic complication of pregnancy, which is associated with significant maternal and fetal morbidity and mortality. case presentation: a 30-year old woman at 24th week of gestation and complaint of pain, contractions and spotting was admitted in royan institute in tehran, iran. she had a past medical his...

Background Chlamydia trachomatis (CT) with damaging effects on sperm quality parameters can often cause infertility in men. Objective The main objective of this study was to determine the diagnostic value of polymerase chain reaction (PCR) and enzyme linked immuno sorbent assay (ELISA) for screening and detecting CT in semen samples of infertile men. Materials and Methods In this cross-sect...

OBJECTIVE After the introduction of assisted reproductive techniques, human embryos were officially introduced into laboratories and now thousands of them are cryopreserved in such settings. Embryonic stem cells and the future application of such cells in the treatment of disease opened the door to further research on human embryos. These developments raise many ethical issues, some of which ha...

BACKGROUND Assessment of uterine abnormalities is a core part in infertility evaluation. OBJECTIVE The aim of this study was to evaluate the sensitivity and specificity of three-dimensional hysterosonography (3-DHS) in the diagnosis of uterine abnormalities in infertile women. MATERIALS AND METHODS The infertile women who visited Royan Institute and referred to 3-DHS consecutively, prior to...

OBJECTIVES The diminished ovarian reserve (DOR) is a condition characterized by a reduction in the number and/or quality of oocytes. This primary infertility disorder is usually accompanied with an increase in the follicle-stimulating hormone (FSH) levels and regular menses. Although there are many factors contributing to the DOR situation, it is likely that many of idiopathic cases have geneti...