The conformational properties of CP-10(42-55), a peptide corresponding to the hinge region of CP-10, were investigated using circular dichroism spectroscopy and reverse-phase high-performance liquid chromatography (RP-HPLC). The circular dichroism studies indicated that CP-10(42-55) formed considerable secondary structure in the presence of hydrophobic solution environments including 50% aceton...

A simple, precise and rapid RP-HPLC method was developed for the simultaneous determination of simvastatin and ezetimibe in combined pharmaceutical dosage forms. The method was carried out on a Shim-pack, RP-C18 column using a mixture of acetonitrile: methanol: buffer (triethylamine pH-3) in the ratio 15:45:40 and detection was done at 240 nm using external standard method as quantitation. The ...

Several flavonoids present in red grape skins from four varieties of Portuguese grapes were determined by reverse-phase high-performance liquid chromatography (RP-HPLC) with electrochemical detection (ECD). Extraction of flavonoids from red grape skins was performed by ultrasonication, and hydrochloric acid in methanol was used as extraction solvent. The developed RP-HPLC method used combined i...

The molecular structure of a variety of novel mercury-phytochelatin complexes was evidenced in rice plants exposed to inorganic mercury (Hg2+) using RP-HPLC with simultaneous detection via ICP-MS and ES-MS.

Objective: Simple, rapid RP-HPLC and HPTLC methods have been developed in order to study the degradation of Roxadustat under various stress conditions. The Kinetics hydrolytic is studied. Methods: Optimum separation its products was achieved using following conditions HPLC, Agilent eclipse XDB-C8 (150×4.6 mm) column, mobile phase composed methanol: phosphate buffer (pH 5, 0.05 M) (70:30 v/v) wi...

Development and Validation of RP-HPLC Method for the Simultaneous Estimation Domperidone Naproxen in Tablet Dosage FormMd. Shozan Mondal, Md. Ahsanul Haque, Mohammad Safiqul Islam, S.M. Ashraful Islam

Development and Validation of RP-HPLC Method for the Simultaneous Estimation Domperidone Naproxen in Tablet Dosage FormMd. Shozan Mondal, Md. Ahsanul Haque, Mohammad Safiqul Islam, S.M. Ashraful Islam

Development and Validation of RP-HPLC Method for the Simultaneous Estimation Domperidone Naproxen in Tablet Dosage FormMd. Shozan Mondal, Md. Ahsanul Haque, Mohammad Safiqul Islam, S.M. Ashraful Islam