We have studied the pattern of axon outgrowth from the identified embryonic Drosophila motorneurons, RP1, RP3, RP4 and RP5, from the onset of axonogenesis to the time of arborization over target muscles. Lucifer Yellow was intracellularly injected into each of these neurons to obtain a detailed description of the morphology of their growth cones and of the pathways that they follow. We have div...

The long latencies introduced by remote accesses in a large multiprocessor can be hidden by caching. Caching also decreases the network load. We introduce a new class of architectures called Cache Only Memory Archi-tectures (COMA). These architectures provide the programming paradigm of the shared-memory architectures, but have no physically shared memory; instead, the caches attached to the pr...

0-efficient triangulations of 3-manifolds are defined and studied. It is shown that any triangulation of a closed, orientable, irreducible 3-manifold M can be modified to a 0-efficient triangulation orM can be shown to be one of the manifolds S3,RP3 or L(3, 1). Similarly, any triangulation of a compact, orientable, irreducible, ∂-irreducible 3-manifold can be modified to a 0-efficient triangula...

The role of nasal endoscopy in the prescription of allergen immunotherapy Key words Allergic rhinitis, allergen immunotherapy, nasal endoscopy. According to the more recent guidelines, allergen specific immunotherapy (SIT), can be prescribed in rhinocon-junctivitis and/or asthma, if an IgE mediated mechanism is well ascertained, if the causal role of a given allergen is uncontrovertibly demonst...

Multicomputer systems are distributed-memory The Cosmic Cube [25], the Finite Element Machine [20], the NCUBE/ten [13], and the Transputer system [30] are examples of multicomputer systems. The Butterfly Parallel Proces-'Or [513 the NYU U1tracomputer [l and the CEDAR system 191 are examples of multiprocessor systems. The IBM RP3 [23] is an example of a hybrid form. This system encompasses both ...

We have previously described the preparation, purification and partial characterization of recombinant (rec) forms of rat luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In the present study, the special functional features of these hormones were studied further, in vitro and in vivo, and compared with human recLH and recFSH, as well as with human urinary choriongonadotropin (h...

PURPOSE Canine X-linked progressive retinal atrophy (XLPRA) is caused by mutations in RPGR exon ORF15, which is also a mutation hotspot in human X-linked retinitis pigmentosa 3 (RP3). The XLPRA1 form of disease has shown extensive phenotypic variability in a colony of dogs that all inherited the same mutant X-chromosome. This variability in onset and severity makes XLPRA1 a valuable model to us...

BACKGROUND Caseating granulomas are often associated with a mycobacterial infection (TB) and are thought to be exceedingly rare in cutaneous leishmaniasis (CL). However, no large series has accurately documented the incidence of caseating granulomas in CL. METHODS A multiregional cohort consisting of 317 patients with CL [Syria (157), Pakistan (66), Lebanon (47), Saudi Arabia (43), Ethiopia (...

Let M be an irreducible, compact, connected, orientable 3-manifold whose boundary is a torus. We show that if M is hyperbolic, then it admits at most six finite/cyclic fillings of maximal distance 5. Further, the distance of a finite/cyclic filling to a cyclic filling is at most 2. If M has a nonboundary-parallel, incompressible torus and is not a generalized 1-iterated torus knot complement, t...

Roughness elements affect internal flows in different ways. One effect is a transition from laminar to turbulent flow at a lower Reynolds number than the predicted Re=2300. Initial work at RIT in the subject area was performed by Schmitt and Kandlikar (2005) and Kandlikar et al. (2005), and this study is an extension of these efforts. The channel used in this study is rectangular, with varying ...