The purpose of this study is to measure and compare the hemolysis produced by roller pumps with varied occlusion settings and a centrifugal pump. The null hypothesis is that there is no difference in the Index of Hemolysis (IH = gm Hb/100 L pumped) produced by a roller pump (RP) at four different occlusion settings and a centrifugal pump (CP) at the same blood flow rate (4.5 L/min) and afterloa...

Everett's theorem-6 of the domain theory was examined by conducting adsorption in situ with small angle x-ray scattering (SAXS) supplemented by the contrast matching technique. The study focuses on the spectrum differences of a point to which the system arrives from different scanning paths. It is noted that according to this theorem at a common point the system has similar macroscopic properti...

Short-radius centrifugation (SRC) provides a practical means of producing artificial gravity for long duration space flights, though perceptual side-effects could limit its operational feasibility. Head turns (HT) during SRC, other than those about the centrifugation axis, produce Cross-Coupled Stimulation (CCS), perceived as a tumbling sensation. CCS can be nauseagenic, though adaptation can m...

AA amyloidosis is a systemic disease that develops secondary to chronic inflammatory diseases Macrophages are often found in the vicinity of amyloid deposits and considered to play a role in both formation and degradation of amyloid fibrils. In spleen reside at least three types of macrophages, red pulp macrophages (RPM), marginal zone macrophages (MZM), metallophilic marginal zone macrophages ...

OBJECTIVE Notch, VEGF, and components of the Hedgehog (Hh) signaling pathway have been implicated in vascular morphogenesis. The role of Notch in mediating hedgehog control of adult vascular smooth muscle cell (SMC) growth and survival remains unexplored. METHODS AND RESULTS In cultured SMCs, activation of Hh signaling with recombinant rShh (3.5 mug/mL) or plasmid encoded Shh increased Ptc1 e...

pro~rpms. T he genera-purpose computing workload is changing to include more processing of multimedia information. We define media processing as the processing of digital multimedia information, such as images. video, audio. 2D and 3D graphics, animation, and text. This multimedia data, at the lowest component level, tend to be 16 bits or less. However, general-purpose microprocessors are gener...

The Federal Facilities Forum is a group of It is imperative that any persons working U.S. Environmental Protection Agency on sites believed to be contaminated with (EPA) scientists and engineers, representing explosive residues thoroughly familiarize EPA regional offices, committed to the themselves with the physical and toxic identification and resolution of issues affectproperties of the mate...

Case Presentation: A 31 year old male with dilated cardiomyopathy and symptoms of New York Heart Association class IV heart failure presented for left ventricular assist device (LVAD) implantation as destination therapy. The patient was admitted to the hospital approximately one month prior with decompensation of his cardiomyopathy and associated liver failure. The patient was stabilized and wa...

The U.S. Environmental Protection Agency (EPA) Engineering Issue papers are a series of documents that summarize the available information on specific contaminants, selected treatment and site remediation technologies, and related issues. This Engineering Issue paper is intended to provide remedial project managers (RPMs), on-scene coordinators (OSCs), contractors, and other state or private re...

AIMS Our aims were to determine the effect of alcohol (EtOH) on endothelial angiogenic activity and to delineate the cell signalling mechanisms involved. METHODS AND RESULTS Treatment of human umbilical vein endothelial cells (HUVECs) with EtOH (1-100 mM, 24 h) dose-dependently increased their network formation on Matrigel (an index of angiogenesis) with a maximum response (2.5- to 3-fold inc...