SYNOPSIS. Selective breeding of house mice has been used to study the evolution of locomotor behavior. Our model consists of 4 replicate lines selectively bred for high voluntary wheel running (High-Runner) and 4 bred randomly (Control). The major changes in High-Runner lines appear to have taken place in the brain rather than in capacities for exercise. Their neurobiological profile resembles ...

Exercise capacity and dietary restriction (DR) are linked to improved quality of life, including enhanced brain function and neuro-protection. Brain derived neurotrophic factor (BDNF) is one of the key proteins involved in the beneficial effects of exercise on brain. Low capacity runner (LCR) and high capacity runner (HCR) rats were subjected to DR in order to investigate the regulation of BDNF...

Numerical simulations were performed to investigate pressure fluctuations in the S-shaped region of a pump-turbine model. Analyses focused on pressure fluctuations in the draft tube and in the gap between the guide vanes and runner. Calculations were made under six different operating conditions with a constant guide vane opening, and the best efficiency point, runaway point, and low-discharge ...

Recent evidence suggests that wheel running can abolish conditioned place preference (CPP) for cocaine in mice. Running significantly increases the number of new neurons in the hippocampus, and new neurons have been hypothesised to enhance plasticity and behavioral flexibility. Therefore, we tested the hypothesis that increased neurogenesis was necessary for exercise to abolish cocaine CPP. Mal...

Relatively few studies have extensively analysed the genetic diversity of the runner bean through molecular markers. Here, we used six chloroplast microsatellites (cpSSRs) to investigate the cytoplasmic diversity of 331 European domesticated accessions of the scarlet runner bean (Phaseolus coccineus L.), including the botanical varieties albiflorus, bicolor and coccineus, and a sample of 49 dom...

Hydropower plants may be required to operate in synchronous condenser mode in order to supply reactive power to the grid for compensating the fluctuations introduced by the intermittent renewable energies such wind and solar. When operating in this mode, the tail water in the Francis turbine or pump-turbine is depressed below the runner by injecting pressurized air in order to spin in air to re...

In recent years, large-capacity, high-head pump–turbine units have been developed for pumped storage power plants to effectively utilise water energy and store large amounts of electricity. Compared with the traditional Francis turbine unit, radial distance between trailing edge guide vanes leading runner blades unit is smaller, so rotor–stator interaction corresponding pressure fluctuations in...

Skeletal muscle-derived stem cells, termed as satellite cells, play essential roles in regeneration after muscle injury in adult skeletal muscle. Diabetes mellitus (DM), one of the most common metabolic diseases, causes impairments of satellite cell function. However, the studies of the countermeasures for the DM-induced dysfunction of satellite cells have been poor. Here, we investigated the e...