Introduction Epicardial mapping revealed the existence of abnormal potentials on the right ventricular outflow tract (RVOT) in patients with Brugada syndrome. It is reported that tissues of the RVOT epicardium from open-chest biopsy and autopsy showed the existence of fibrosis and fatty infiltration associated with increased interstitial collagen and decreased connexin 43. Although the abnormal...

A 40-year-old man with known hypertrophic cardiomyopathy presented with syncope after coughing. Physical examination revealed a systolic murmur that was accentuated by the Valsalva maneuver. An electrocardiogram suggested biventricular hypertrophy and biatrial enlargement (Fig. 1). Echocardiograms revealed asymmetric septal hypertrophy with a diastolic septal thickness of 2.3 cm, and evidence o...

Palliative surgery for conotruncal congenital cardiovascular defects such as tetralogy of Fallot and truncus arteriosus includes reconstruction of the right ventricular (RV) outflow tract (RVOT). Depending on patient age, anatomy, and other factors, a variety of techniques, prosthetic materials, and valves are used to reconstruct the RVOT, but essentially all become dysfunctional over time, wit...

Palliative surgery for conotruncal congenital cardiovascular defects such as tetralogy of Fallot and truncus arteriosus includes reconstruction of the right ventricular (RV) outflow tract (RVOT). Depending on patient age, anatomy, and other factors, a variety of techniques, prosthetic materials, and valves are used to reconstruct the RVOT, but essentially all become dysfunctional over time, wit...

BACKGROUND Brugada syndrome (BrS) is characterized by a typical ECG pattern. We aimed to determine the pathophysiologic basis of the ST-segment in the BrS-ECG with data from various epicardial and endocardial right ventricular activation mapping procedures in 6 BrS patients and in 5 non-BrS controls. METHODS AND RESULTS In 7 patients (2 BrS and 5 controls) with atrial fibrillation, an epicard...

BACKGROUND The aim of this study was to investigate the different substrate characteristics of repetitive premature ventricular complexed (PVC) trigger sites by the non-contact mapping (NCM). METHODS Thirty-five consecutive patients, including 14 with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC) and 21 with idiopathic right ventricular outflow tract tachycardia (RVOT VT), ...

OBJECTIVES The purpose of this study was to evaluate whether electrocardiographic characteristics of ventricular arrhythmias distinguish patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) from those with right ventricular outflow tract tachycardia (RVOT-VT). BACKGROUND Ventricular arrhythmias in RVOT-VT and ARVD/C-VT patients can share a left bundle branch block/...

is the most common birth defect, affecting one in every 125–150 births, with approximately 40,000 children diagnosed with CHD every year in the United States. As a result of dramatic improvements in survival seen over the past several decades, there are now an estimated 1.5–2.0 million adults with CHD in the United States. When grouped together, lesions that require surgical correction of the r...

BACKGROUND Few studies have discussed gender differences in idiopathic right ventricular outflow tract-ventricular tachycardia (RVOT-VT). This study explored possible gender differences in electrophysiological characteristics and catheter ablation for idiopathic RVOT-VT in Taiwan. METHODS Ninety-three patients (mean age 38.7 ± 15.5years, 30 males) were diagnosed as having idiopathic RVOT-VT b...

Prolonged pacing from the right ventricular (RV) apex has been shown to be associated with progressive left ventricular dysfunction as demonstrated by heart failure, atrial fibrillation and an increased morbidity and mortality [1-6]. This has led to an interest in alternate RV pacing sites and in particular the mid RV septum and the RV outflow tract (RVOT) septum [7-11]. These sites are theoret...