Simulations based on disease-progression models and phase II trial results can predict phase III results and have the potential to improve oncology drug development by informing end-of-phase II decisions (EOP2Ds). Many barriers impede effective use of modeling and simulation (M&S) for EOP2Ds in oncology: concerns about model validity, lack of access to M&S results and patient-level data, limite...

As a coagulase negative Staphylococcus species, S. caprae is not considered as a clinically-significant member, unlike S. epidermidis. In this report, we describe a case of sepsis resulting from S. caprae infection. This relatively young woman was in generally good health and contracted S. caprae most probably during her treatment of an acute pulmonary embolism. The purpose of this report is to...

introduction: primary schools are children's first social environments. other people's attitudes towards environmental hazards play a key role in developing children's personality. this study aimed to identify and assess the environmental risks (such as emission of pollutants into the air, discharge of pollutants into water and soil, energy consumption, etc.) in shohadaye kork gi...

OBJECTIVE To evaluate an insurance awareness campaign carried out before the launch of three community-based health insurance (CBHI) schemes in rural India, answering the questions: Has the awareness campaign been successful in enhancing participants' understanding of health insurance? What awareness tools were most useful from the participants' point of view? Has enhanced awareness resulted in...

Four basic approaches that have been used to demonstrate perception without awareness are described. Each approach re ̄ects one of two types of experimental logic and one of two possible methods for controlling awareness. The experimental logic has been either to demonstrate a dissociation between a measure of perception with awareness and a measure that is sensitive to perception without awaren...

Intraoperative awareness, with or without recall, continues to be a topic of clinical significance and neurobiological interest. In this article, we review evidence pertaining to the incidence, sequelae, and prevention of intraoperative awareness. We also assess which aspects of the complication are well understood (i.e. non-controversial) and which require further research for clarification (i...

Employees’ information security awareness (ISA) is a key antecedent of information security behavior. However, to date we know very little about the factors that are responsible for some employees having a higher level of ISA than others. Our study addresses this gap. We propose a model that comprises institutional, individual, and environmental factors preceding ISA. The model was empirically ...