نتایج جستجو برای: s tnf

تعداد نتایج: 761629  

Journal: :Infection and immunity 2003
Yael Yuhas Abraham Weizman Shai Ashkenazi

We have previously demonstrated that pretreatment of mice with Shigella dysenteriae sonicate enhanced their susceptibility to pentylenetetrazole-induced seizures and that tumor necrosis factor alpha (TNF-alpha) was proconvulsive in this respect. The present study shows that TNF-alpha, at high concentrations, may also exert a suppressive effect on Shigella-mediated seizures. This implies that hi...

Journal: :Infection and immunity 1999
A W Cheever R W Poindexter T A Wynn

Mice with severe combined immunodeficiency (SCID mice) lack functional B and T cells. Egg laying by Schistosoma mansoni and S. japonicum was delayed in SCID mice, but in a matter of weeks worm fecundity was equivalent to that in intact mice. SCID mice formed smaller hepatic granulomas and showed less fibrosis than did intact mice. The reduction in egg-associated pathology in SCID mice correlate...

Journal: :Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 2015
Hadi Sarir Ghodsieh Emdadifard Homayoun Farhangfar Hossein TaheriChadorneshin

AIM AND SCOPE The anti-inflammatory effect of vitamin E under moderate exercises has been evaluated. However, the effect of vitamin E succinate, which has more potent anti-inflammatory effect than other isomers of vitamin E has not been evaluated. Therefore, the aim of the present study was to evaluate the effects of vitamin E succinate on tumor necrosis factor alpha (TNF-α) and interleukin-6 (...

2012
Xin Guo Xu Huang Yi-song Wu Dong-hai Liu Hong-li Lu Yong-chul Kim Wen-xie Xu

PURPOSE To investigate the role of endogenous hydrogen sulfide (H(2)S) in partial obstruction-induced dysfunction of the interstitial cells of Cajal (ICC) in mice ileum. MATERIALS AND METHODS Partial intestinal obstruction was induced surgically in male imprinting control region (ICR) mice. ICC networks were studied by Immunohistochemistry. Electrical activity was recorded by intracellular re...

Journal: :The American journal of physiology 1999
Vidya Mohamed-Ali Steven Goodrick Karen Bulmer Jeffrey M P Holly John S Yudkin Simon W Coppack

To investigate in vivo adipose tissue production of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and their soluble receptors: TNF receptor type I (sTNFR-I), TNF receptor type II (sTNFR-II), and IL-6 receptor (sIL-6R), we determined arteriovenous differences in their levels across abdominal subcutaneous adipose tissue in obese subjects. Subjects had a median (interquartile range) age o...

Journal: :Molecules 2015
Özlem Bahadır Acikara Jan Hošek Petr Babula Josef Cvačka Miloš Budešínský Martin Dračinský Gülçin Saltan İşcan Daniela Kadlecová Ludmila Ballová Karel Šmejkal

Scorzonera species are used in different folk medicines to combat many diseases, including the illnesses connected with inflammation. Previous experiments showed anti-inflammatory activity of Scorzonera extracts in vivo. S. latifolia, S. cana var. jacquiniana, S. tomentosa, S. mollis ssp. szowitsii, S. eriophora, S. incisa, S. cinerea, and S. parviflora extracts were, therefore, evaluated for t...

2014
Kariuki H Njaanake Paul E Simonsen Birgitte J Vennervald Dunstan A Mukoko Claus M Reimert Kimani Gachuhi Walter G Jaoko Benson B Estambale

BACKGROUND Pathological changes due to infection with Schistosoma haematobium include cytokine-mediated urinary tract inflammation. The involved cytokines may be excreted in urine and their presence in urine may therefore reflect S. haematobium-related urinary tract pathology. The present study, for the first time, reports on the relationship between selected cytokines in urine and infection wi...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2009
Yanfei Wang Xia Zhao Hongfang Jin Hongling Wei Wei Li Dingfang Bu Xiuying Tang Yali Ren Chaoshu Tang Junbao Du

OBJECTIVE We explored the effect of hydrogen sulfide (H(2)S) on atherosclerotic progression, particularly on intracellular adhesion molecule-1 (ICAM-1) in apolipoprotein-E knockout (apoE(-/-)) mice and human umbilical vein endothelial cells (HUVECs). METHODS AND RESULTS ApoE(-/-) mice were treated with sodium hydrosulfide (NaHS) or DL-propargylglycine (PPG); HUVECs were pretreated with NaHS. ...

Journal: :Journal of immunology 2010
Cherrie-Lee Small Christopher R Shaler Sarah McCormick Mangalakumari Jeyanathan Daniela Damjanovic Earl G Brown Petra Arck Manel Jordana Charu Kaushic Ali A Ashkar Zhou Xing

Influenza viral infection is well-known to predispose to subsequent bacterial superinfection in the lung but the mechanisms have remained poorly defined. We have established a murine model of heterologous infections by an H1N1 influenza virus and Staphylococcus aureus. We found that indeed prior influenza infection markedly increased the susceptibility of mice to secondary S. aureus superinfect...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده تربیت بدنی و علوم ورزشی 1390

زمینه و هدف: ورزش های مقاومتی، اثرات متفاوتی بر بیماران دیابتی نسبت به ورزش های هوازی دارند. هدف از مطالعه حاضر تاثیر تمرین مقاومتی منظم بر روی سطوح پلاسمایی سایتوکاین های tnf-?و il-18 در رتهای سالم و دیابتی بود. روش بررسی: برای اجرای این مطالعه 32 رت سه ماهه از نژاد ویستار(محدوده وزنی 30±250گرم)انتخاب و به طور تصادفی به چهار گروه 8 تایی تقسیم شدند. جهت ایجاد دیابت در 17 موش از روش تزریق داخل ...

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