This note describes the design, fabrication, and testing of a novel microelectromechanical systems Coulter counter. The Coulter counter will be used to detect and monitor impedance changes of cells as a function of time in response to different experimental extracellular environments. The device consists of SU-8 (negative photoresist) microchannels, vertical electroplated electrodes, polydimeth...

OBJECTIVE To determine the utility of inhaled hypertonic saline solution to treat infants hospitalized with viral bronchiolitis. DESIGN Randomized, double-blind, controlled trial. Fifty-two hospitalized infants (mean +/- SD age, 2.9 +/- 2.1 months) with viral bronchiolitis received either inhalation of epinephrine, 1.5 mg, in 4 mL of 0.9% saline solution (group 1; n = 25) or inhalation of epi...

It was Sir Ranald Martin who, if I remember aright, said that every method of treatment has been successful in the hands of the man who introduced it; but in presenting this series of over 100 consecutive cases of dj'sentery treated b}7 sulphate of magnesium, this fallacy will not appear, as I have no claims to be the introducer. In fact, as I have shown in another place,* the method appears to...

cialist in the medical critical care/pulmonary unit at Christiana Care Health System in Newark, Delaware. history of smoking along with chronic respiratory diseases such as cystic fibrosis, chronic obstructive pulmonary disease, asthma, and bronchiectasis. Other patient-related factors that may contribute include smoking, immobility, sedation, muscle weakness, and dehydration. A mucous plug occ...

The review by Oliveira and colleagues on the subject of hypertonic saline resuscitation in sepsis (included in the present issue) suggests possible benefits for hypertonic saline. There is a firm experimental basis for the actions of hypertonic saline/hyperoncotic solutions in hemorrhagic hypotension, which include expansion of blood volume, improvement in cardiac index, favorable modulation of...

We report the case of an athletic 49-year-old female who has run the 2011 Marathon of Paris and was addressed to the hospital for a confusion. The investigations revealed a cerebral edema complicating a severe hyponatremia secondary to an exercise-associated hyponatremia (EAH). Using 3% hypertonic saline solution, the evolution the patient rapidly improve allowing discharge after 7 days. We the...

Toads (Bufo arenarum) were exposed to pairings between immersion in a neutral saline solution (i.e., one that caused no significant variation in fluid balance), followed by immersion in a highly hypertonic saline solution (i.e., one that caused water loss). In Experiment 1, solutions were presented in a Pavlovian conditioning arrangement. A group receiving a single neutral-highly hypertonic pai...

transfusions. The constant bleeding, together with the constant replenishment by saline solution, must have acted by washing the toxin out of the tissues, as it were. The bleeding stopped as soon as the venom was sufficiently diluted. Calcium was therefore contraindicated, contrary to your suggestion in the footnote. The idea strikes me that it stands to reason to try to treat both colubrine an...

An investigation of malaria in a US patient without recent travel established Plasmodium falciparum molecular genotype identity in 2 patients who shared a hospital room. P. falciparum can be transmitted in a hospital environment from patient to patient by blood inoculum if standard precautions are breached.

CO2 Storage in Saline Aquifers — Saline aquifers represent a promising way for CO2 sequestration. Storage capacities of saline aquifers are very important around the world. The Sleipner site in the North Sea is currently the single case world-wide of CO2 storage in a saline aquifer. A general review is given on the specific risks for CO2 storage in saline aquifer. The regional distribution of C...