Introduction: Radioisotope scanning is the best method for objective assessment of salivary gland function. Thus, it was used in a randomized trial of concomitant pilocarpine for assessment of radiation-induced xerostomia, in addition to subjective evaluation by an approved questionnaire and objective standard xerostomia grading. Methods: Patients randomized in placebo-controlled trial of...

OBJECTIVES To determine the expression level of the Wnt components-WIF1 (Wnt inhibitory factor 1), WNT1, and beta-catenin-in salivary gland tumor cells and to investigate the mechanisms that contribute to activation of the Wnt pathway in human salivary gland tumors. DESIGN The expression of WIF1, WNT1, and beta-catenin in salivary gland normal tissue and tumor cell lines was analyzed by rever...

Salivary gland tumors are among the pathologies in the head and neck that may be challenging in diagnosis and treatment. Most benign tumors occur in the parotid gland. Pleomorphic Adenoma is the most common type. Basal Cell Adenoma is a subtype of the Monomorphic Adenoma with rare occurrence. Proper diagnosis and clinical evaluation by the use of radiography can lead the physician to the best t...

introdouction: mucoepidermoid carcinoma (mec) is one of the most common salivary gland malignancies. the prevalence of salivary gland tumors varies in different geographic areas. in this report, we evaluated the prevalence of mec in iran and compared it with that previously reported in other countries. materials and methods: the files of oral pathology, shahid beheshti university of medical sci...

BACKGROUND Sialolithiasis is a common disease of salivary glands. The etiology of these calculi is little known and their exact mechanism of formation is unknown. METHODS The composition and structure of 21 sialoliths were studied and the composition of the saliva of each corresponding patient was determined (pH, calcium, magnesium, phosphorus, citrate and phytate). RESULTS Eighteen sialoli...

Patients with salivary gland disease most frequently present with complaints of oral dryness, swelling, or a mass in a gland. This chapter first reviews briefly the anatomy and physiology of the salivary glands and then outlines a diagnostic approach to the patient who has signs and symptoms that are suggestive of salivary gland dysfunction. The examination of a patient with dry mouth is descri...

Salivary gland tumors are rare and account for 2-3% of tumors occurring in the head and neck. Pleomorphic adenoma is a benign neoplasm which is commonly encountered in the parotid gland and other major salivary glands. At times they can also develop in minor salivary glands of the palate. The majority of minor salivary gland tumors are malignant. This case report describes a case of mixed tumor...

BACKGROUND Dysgenetic polycystic salivary gland disease is a rare pathology. No case of minor salivary gland involvement has been reported in the literature. METHODS A female patient presented with bilateral tumors of the parotid glands, bilateral submandibular gland enlargement, and multiple cystic lesions of the oral mucosa. MRI of the neck was performed along with fine-needle aspiration (F...

Major salivary gland absence is a rare disorder. The cause of congenital absence of the salivary glands has not been determined, but it may be associated with ectodermal defects of the first and second branchial arches. Isolated absence of a unilateral submandibular gland is an unusual entity with less than ten cases reported in the literature. The etiopathogenesis of isolated absence of a majo...