Diclofenac 2(2,6 dichloranilino) phenylacetic acid is a widely prescribed non-steroidal anti inflammatory drug. It is used to reduce pain and treat inflammation in some disorders like rheumatoid arthritis, osteoarthritis, ankylosing spondilytis, gout, dysmenorrhea, spondylarthritis etc., It acts by inhibiting the action of cycloxygenase enzymes COX-1 and COX-2 which are responsible for the synt...

The antimicrobial activity of methanol and acetone extracts of Butomus umbellatus, Polygonum amphibium, and two species of the genus Sparganium (S. erectum and S. emersum)against three Gram-positive, five Gram-negative bacteria and one fungus was assessed by the disk diffusion method. The microorganisms used were Staphylococcus aureusATCC-29740, Escherichia coli ATCC-25922, Pseudomonas aerugino...

The presence of concomitant bacteria was assessed in the blood of 125 malaria positive patients and 60 malaria negative controls, resident in Owerri, southeastern Nigeria. Blood samples were cultured in MacConkey, Chocolate and Blood agar, respectively using oxoid signal system after the manufacturer's instructions. Blood cultures of 44 (35.2%) of the 125 malaria positive patients had bacterial...

Treatments of bacterial infections have become a difficult task in the medical practice due to high level of resistance to the existing marketed antibiotics. This problem evoked us to search for new antimicrobial agent for better management of bacterial infections. The present study was carried out to evaluate antimicrobial properties of epidermal mucus (soluble mucin or s-mucin). s-mucin was e...

Antibacterial activities of different forms of peppermint (Mentha piperita) viz., aqueous infusion, decoction, juice and essential oil were investigated against 100 isolates belonging to 11 different species of Gram –ve bacilli viz., Escherichia coli (30), Klebsiella pneumoniae (25), Pseudomonas aeruginosa (15), Salmonella typhi (5), S. paratyphi A (1), S. paratyphi B (1), Proteus mirabilis (10...

Two biologically active Schiff bases, C13H10BrON (4), C13H9Br2O2N (5), were synthesized by the reaction of 2-aminophenol (1) with 3-bromobenzaldehyde (2) or 3,5-dibromo-4hydroxybenzaldehyde (3) in the presence of conc. H2SO4. The characterization of Schiff bases were carried out by using spectroscopic techniques including IR, H-NMR, FAB-MS along with elemental analyses. The Schiff bases were ch...

Solanum trilobatum Linn. is extensively used in Indian traditional and folklore medicines to cure various human ailments. The preliminary phytochemical screening of the leaves revealed the presence of Sugar, Protein, Alkaloids, Flavonoids, Saponins, Tannins, Cardiac glycoside, Terpenoids and Lipids. In vitro antibacterial studies on the leaf extracts were carried out on eight medically importan...

The mother tinctures of desert were screened for antibacterial activity against bacterial strains of Gram-positive and Gram-negative bacteria. Mother tinctures were prepared by maceration process and antibacterial activity of different plants was evaluated and compared by measuring their zones of inhibition. The results indicated that Boerrhavia diffusa mother tincture had excellent activity on...

The synthesis and characterization of cadmium and mercury complexes of selenocyanate of the type [(L)M(SeCN)2] are described, where L is L-Histidine (His) or L-Glycine (Gly) and M is Cd(2+) or Hg(2+). These complexes are obtained by the reaction of 1 equivalent of respective amino acids with metal diselenocyanate precursor in a mixture of solvents (methanol : water = 1 : 1). These synthesized c...