In the course of our search for antimalarial leads from marine algae, four metabolites, sargaquinoic acid, sargahydroquinoic acid, sargaquinal and fucoxanthin, were isolated from the South African alga Sargassum heterophyllum. Fucoxanthin and sargaquinal showed good antiplasmodial activity toward a chloroquine-sensitive strain (D10) of Plasmodium falciparum (IC50 1.5 and 2.0 microM, respectivel...

An investigation of the natural products chemistry of the brown alga Sargassum asperifolium from the red sea yielded a new steroidal metabolite, 24-vinyl cholest-4-ene-24-ol-3-one, saringosterone (3), a known steroidal metabolite, 24-vinyl cholest-5-ene-3b,24-diol, saringosterol (4), and known diterpene with a hydroazulene skeleton, dictyone (1). The identification of the isolated metabolites w...

Two new sesquiterpenes, 1β,5α,6α,14-tetraacetoxy-9α-benzoyloxy-7β H-eudesman-2β,11-diol (1) and 4α,5α-diacetoxy-9α-benzoyloxy-7βH-eudesman-1β,2β,11, 14-tetraol (2), were produced as stress metabolites in the cultured mycelia of Pestalotiopsis sp. Z233 isolated from the algae Sargassum horneri in response to abiotic stress elicitation by CuCl2. Their structures were established by spectroscopic ...

A new species of the genus Paracaprella is described based on the specimens associated with the algae Sargassum cymosum and Laurencia obtusa that were collected from infralittoral depths (0.5 to 3.0 m) at Sepultura Beach, Bombinhas and Paciência Beach, Penha, Santa Catarina State, Brazil. This new species differs from the others of the genus by the unique morphology of the males' gnathopod 2: i...

The Turks and Caicos Islands (TCI) have been affected by sargassum inundations, with impacts on the economy environment. Sargassum removal can be costly, but use valorisation may generate income offset environmental damage. A significant barrier to of is insufficient knowledge its chemical makeup, as well seasonal variation decay after stranding. characterisation mixed constituent species morph...

Sargassum spp. blooms exacerbated by climate change and agricultural runoff are inundating Caribbean beaches, emitting toxic fumes greenhouse gases through decomposition. This hurts tourism, artisanal fishing, shore-based industry, human health, standards-of-living, coastal ecology, the global climate. Barriers, collection machinery, valorization have been unable to provide sufficient, sustaina...

Over the past decade unprecedented blooming of pelagic Sargassum has occurred across Equatorial Atlantic from West Africa to Caribbean. Although mats are considered beneficial in open ocean, providing valuable habitat for a diverse array endemic and associated species, they also inundate coastal areas cause plethora management challenges fisheries, tourism, nearshore ecosystems, public health s...