New information technology developments continue to have a significant impact on large-scale architectural/engineering/construction (A/E/C) projects. However, the issue of whether A/E/C organizations are receiving adequate returns from their information technology (IT) investments remains an important managerial concern. Earlier work on financial models has concentrated on firm-wide strategies ...

The inherent complexity of large-scale information integration efforts has led to the proliferation of numerous metadata capabilities to improve upon project management, quality control and governance. In this paper, we utilise complex information integration projects in the context of SAP application consolidation to analyse several new metadata capabilities, which enable improved governance a...

XP is a code-oriented, light-weight software engineering methodology, suited merely for small-sized teams who develop software that relies on vague or rapidly changing requirements. Being very code-oriented, the discipline of systems engineering knows it as approach of incremental system change. In this contribution, we discuss the enhanced version of a concept on how to extend XP on large scal...

Data migration projects might sound exotic. They are not. Instead, they are common in all medium and large enterprises, e.g., when replacing applications with new (standard) software or when consolidating the IT landscape in the aftermath of mergers and acquisitions activities. Generalpurpose methodologies such as Scrum focus on managing projects. However, they do not discuss (data-migration) d...

This paper proposes a non-interactive system for reducing the level of OCR-induced typographical variation in large text collections, contemporary and historical. Text-Induced Corpus Clean-up or ticcl (pronounce ’tickle’) focuses on high-frequency words derived from the corpus to be cleaned and gathers all typographical variants for any particular focus word that lie within the predefined Leven...

Good accessibility of publicly funded research data is essential to secure an open scientific system and eventually becomes mandatory [Wellcome Trust will Penalise Scientists Who Don't Embrace Open Access. The Guardian 2012]. By the use of high-throughput methods in many research areas from physics to systems biology, large data collections are increasingly important as raw material for researc...

Evaluation is an integral component of quality improvement and there is much to be learned from the evaluation of small scale quality improvement initiatives at a local level. This type of evaluation is useful for a number of different reasons including monitoring the impact of local projects, identifying and dealing with issues as they arise within a project, comparing local projects to draw l...

UNLABELLED The Web-Based GeneChip Analysis System (WGAS) is developed to overcome limitations in analysis setup efficiency, data and procedure sharing, as well as security issues in existing commercial and public domain solutions. It also incorporates unique functions and resources for more accurate and flexible GeneChip analysis. AVAILABILITY WGAS is freely available at: http://arrayanalysis...

A problem in many sequencing projects is the final closure of gaps left in the clone libraries, which serve as templates for sequencing, because of uncloned or unclonable genomic areas. By use of the Xylella fastidiosa genome as a test system, we present here an approach to generate, in a directed manner, sequence information from those gaps. We suggest using the complete clone library as a com...

Many modern new product development (NPD) embedded software projects are required to be run under turbulent conditions. Both the business and the technological environments are often volatile. Uncertainty is then an inherent part of the project management. In such cases, traditional detailed up-front planning with supporting risk management is often inadequate, and more adaptive project managem...