The burden of Crohn’s disease and ulcerative colitis is substantially increased by extraintestinal manifestations (EIMs). In addition to EIMs, there is very rare occurrence of autoimmunopathies like Henoch-Schönlein purpura (HSP) in inflammatory bowel disease. HSP is an inflammatory disease damaging small vessels by immune complex depositions, and affects the skin, joint, kidneys and gastrointe...

Schönlein-Henoch purpura may be complicated by hypoproteinaemia, which in most patients is due to the development of nephrotic syndrome. However, in some proteinuria is insignificant and enteric protein loss has been suggested as the cause. A case with supportive evidence for this is reported.

Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness.

Acute urinary retention secondary to vasculitic penile swelling in children is extremely rare. Henoch-Schönlein purpura is a self-limiting IgA-mediated cutaneous vasculitis, which can cause soft tissue edema. Acute urinary retention requires urgent intervention to prevent obstructive uropathy. Suprapubic catheterization provides an effective management strategy in the emergency setting.

SHARE – workpackage 5: evidence-based recommendations for diagnosis and treatment of kawasaki disease and henoch schönlein purpura Nienke de Graeff, Noortje Groot, Sylvia Kamphuis, Tadej Avcin, Brigitte Bader-Meunier, Pavla Dolezalova, Brian Feldman, Isabelle Kone-Paut, Pekka Lahdenne, Alberto Martini, Liza McCann, Clarissa Pilkington, Angelo Ravelli, Annet van Royen, Nico Wulffraat, Seza Ozen,...

Dr. J.-C. Davin, Service de Pédiatrie, Bât. 35, CHU Sart-Tilman, B-4000 Liège 1 (Belgium) Dear Sir, In 1988, we demonstrated an increased intestinal permeability to [51Cr]EDTA in some children presenting with idiopathic IgA nephropathy or with Henoch-Schönlein purpura nephritis [1]. Three further studies of intestinal permeability were reported in adult idiopathic IgA nephropathy [2-4]. Two [2,...

Recent developments in relation to Henoch-Schönlein purpura (HSP) include: a) a proposed new classification of childhood vasculitides including new classification criteria for HSP; b) the identification of various, potentially important, genetic polymorphisms in HSP that may be relevant in terms of predisposition to or protection from complications; c) evidence that prophylactic steroid at the ...

BACKGROUND The most appropriate management of Henoch-Schönlein Purpura (HSP) nephritis with nephrotic-range proteinuria remains uncertain. The aim of this study was to evaluate the clinical therapeutic effects of mycophenolate mofetil and low-dose steroid in Henoch-Schönlein purpura nephritis (HSPN) with nephrotic-range proteinuria and pathological classification less than IV in children. MATER...

Henoch-Schönlein purpura (HSP) is a common childhood systemic vasculitis with clinical characteristics of cutaneous palpable purpura, arthralgia/arthritis, bowel angina, and hematuria/proteinuria. HSP is identified mainly based on the above presentations. Combined with pathohistological findings of leukocytoclastic vasculitis (LCV) and IgA-immune deposits in vessel walls and/or glomeruli increa...

A rare case of polyangiitis overlap syndrome is described. The patient was a 25-year-old man who had palpable purpura on his legs which showed leukocytoclastic vasculitis, and polyarteritis nodosa. Superior mesenteric arteriography showed microaneurysms in jejunal branches with focal segmental necrotizing arteritis of small and medium sized muscular arteries in the jejunum. Deposits of IgA and ...