نتایج جستجو برای: schizophrenia disorder
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BACKGROUND Atrial fibrillation (AF) is increasingly prevalent in society, and can elevate cardiac morbidity and mortality. Psychosis and gender are known to play important roles in the genesis of AF. However, it is not clear whether gender modulates the impact of different psychoses on the occurrences of AF. METHODS We identified patients suffering from bipolar disorder and schizophrenia, wit...
BACKGROUND Schizophrenia and bipolar disorder are chronic debilitating disorders that are often treated with second-generation antipsychotic agents, such as aripiprazole, quetiapine, and ziprasidone. While patients who are hospitalized for schizophrenia and bipolar disorder often receive these agents at discharge, comparatively little information exists on subsequent patterns of pharmacotherapy...
BACKGROUND Language use is often disrupted in patients with schizophrenia; novel computational approaches may provide new insights. AIMS To test word use patterns as markers of the perceptual, cognitive and social experiences characteristic of schizophrenia. METHOD Word counting software was applied to first-person accounts of schizophrenia and mood disorder. RESULTS More third-person plu...
BACKGROUND Adversities operating over intrauterine life have been associated with risk of schizophrenia, but the biology of resultant developmental perturbation is poorly understood. AIMS To examine the relationship of congenital anomalies and related functional impairments in infancy to risk of schizophrenia. METHOD Using the Congenital Anomalies data-set from the Prenatal Determinants of ...
OBJECTIVE Brain structural changes in schizoaffective disorder, and how far they resemble those seen in schizophrenia and bipolar disorder, have only been studied to a limited extent. METHOD Forty-five patients meeting DSM-IV and RDC criteria for schizoaffective disorder, groups of patients with 45 matched schizophrenia and bipolar disorder, and 45 matched healthy controls were examined using...
OBJECTIVE Schizophrenia and bipolar disorder are characterized by the presence of neurocognitive impairments on the psychosis continuum. The present study aimed to explore the shared and distinct endophenotypes between these disorders. METHODS The study included 34 probands with remitted schizophrenia and 34 probands with euthymic bipolar disorder who had a history of psychotic symptoms that ...
BACKGROUND: According to recent research, it is still more evident that patients with schizophrenia also suffer from anxiety disorders. Although there is a significant clinical relevance, the impact of anxiety disorders in patients with schizophrenia remains poorly understood. METHOD: A literature search was conducted via Medline and Web of Science using key words relating to schizophrenia and ...
Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia.
CONTEXT Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including neuropsychiatric disorders such as schizophrenia and autism. The possible involvement of copy number variants (CNVs) in bipolar disorder has received little attention to date. OBJECTIVES To determine whether large (>100,000 base pair...
Deficits in language production and comprehension are characteristic of schizophrenia. To date, it remains unclear whether these deficits arise from dysfunctional linguistic knowledge, or predictions derived the context. Alternatively, could be a result neural tracking auditory information resulting decreased fidelity even distorted information. Here, we discuss possible ways for clinical neuro...
There is evidence that premorbid adjustment can differentiate schizophrenia from schizoaffective disorder. We recruited 41 patients with schizophrenia and 24 patients with schizoaffective disorder without substance abuse 6 months before the assessment. Diagnoses were based on the Structured Clinical Interview for DSM-IV. Psychotic symptoms were rated with the Positive and Negative Syndrome Scal...
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