INTRODUCTION Multiple distinct tumors arising in a single individual or within members of a family raise the suspicion of a genetic susceptibility disorder. CASE PRESENTATION We present the case of a 52-year-old Caucasian woman diagnosed with sebaceous gland carcinoma of the eyelid, followed several years later with subsequent diagnoses of breast cancer and papillary carcinoma of the thyroid....

DISEASE HISTORY Sixty-five year-old female, brown skin, married, housewife, natural of Paraíba and coming from Praia Grande, SP, sought a Dermatology outpatient clinic with the complaint of a "nodule on the tip of the nose" for six months, which presented with rapid and progressive growth. Personal and familar history: Virchowian Leprosy in the 15 month of treatment with Multibacillary Multidru...

"Muir-Torre syndrome, a subtype of Lynch is rare genetic disorder. We present the case female patient with long family and personal history who was diagnosed numerous benign malignant tumours various histology, including some sebaceous features, beginning at age 41. The majority were cutaneous tumours, treated complete resection, but they frequently recurred. Visceral cancers included endocervi...

Syringocystadenoma papilliferum (SP) commonly arises in conjunction with nevus sebaceous. Other less common lesions reported with SP include apocrine adenoma, condyloma acuminatum, hidradenoma papilliferum associated with hidrocystoma, poroma folliculare, and a single case ofverrucous carcinoma. We report the second case of verrucous carcinoma in conjunction with SP.

OBJECTIVE Sebaceous Carcinoma is a rare and aggressive malignant tumor. We present a case report of a large truncal tumor with multicentricity and aggressive locoregional recurrence that required trapezius myocutaneous flap reconstruction. Examining patterns of multicentricity, metastasis, and recurrence of sebaceous carcinoma in the literature we sought to explore potential reasons behind the ...

Although nevus sebaceous (NS) is known to develop various types of secondary neoplasms, it rarely causes carcinoma and only fifteen cases of secondary squamous cell carcinoma (SCC) have been reported. We report a rare variant of SCC (acantholytic type) arising in nevus sebaceus.