The present edition of large subunit (LSU; 23S and 23S-like) rRNA secondary structures updates and refines the collections of 1988 [1] and 1990 [2]. As in [1] and [2], each LSU rRNA sequence is presented as a secondary structure, a two-dimensional format that represents, in part, the biologically relevant conformation of the rRNA molecule. When LSU rRNA sequences are configured in this manner, ...

In many case-control genetic association studies, a secondary phenotype that may have common genetic factors with disease status can be identified. When information on the secondary phenotype is available only for the case group due to cost and different data sources, a fitting linear regression model ignoring supplementary phenotype data may provide limited knowledge regarding genetic associat...

Using data from Indonesia, this paper evaluates the impact of school type on academic achievement of junior secondary school students (grades 7-9). Students that graduate from public junior secondary schools, controlling for a variety of other characteristics, score 0.15 to 0.3 standard deviations higher on the national exit exam than comparable privately-schooled peers. This finding is robust ...

This study aims to determine the effect of free cash flow, management ownership, and institusional ownership debt policy with investment opportunity set as a moderating variable manufacturing companies listed on Indonesia Stock Exchange period 2017 2019. Variables used in this research is an independent variable, dependent variable. was performed Exchange. conducted at 24 that meet criteria sam...

AIM To study the role of mRNA secondary structure stability in antisense drug design and obtain better antisense candidates against neu/HER-2/erbB-2 mRNA than previous report. METHODS Program RNAstructure was utilized to simulate the secondary structures of HER-2 mRNA. Then 21 antisense phosphorothioate oligodeoxynucleotides (S-ODN) targeting different parts of secondary structural motif were...

We consider a statistical multiplexer which is modeled as a discrete-time single-server queueing system. Messages consisting of a variable number of fixed-length packets arrive to the multiplexer at the rate of one packet per slot (“train arrivals”), which results in what we call a primary correlation in the packet arrival process. The distribution of the message lengths (in terms of packets) i...

Histologic evaluation of neoadjuvant chemotherapy effect is a well-established prognostic indicator in osteosarcoma and Ewing sarcoma arising in bone. Although tumor necrosis is a primary histologic response for the treatment, secondary degenerative changes following necrosis are frequently shown in those tumors. We reviewed some cases of Ewing sarcoma and osteosarcoma of bone with variable his...

Several autoimmune diseases have been reported to be associated with common variable immunodeficiency disease (CVID), including rheumatoid arthritis and Sjögren's syndrome. On the other hand, approximately 20-30% of patients with rheumatoid arthritis develop secondary Sjögren's syndrome. A 26-year-old woman had a 6-year history of chronic symmetric polyarthritis and 3-year history of sicca synd...

A Monte Carlo method is presented which can obtain the correct tertiary fold of a protein given the secondary structure and as few as three interactions between each secondary structure unit. This method was used to fold hemerythrin, flavodoxin, bovine pancreatic trypsin inhibitor and a variable light domain from an immunoglobulin using the known secondary structures of these proteins. Each of ...