This article is a Commentary on Yang et al. (2021), 231: 2200–2214. Manganese (Mn) an essential element for plants, playing major roles as co-factor of enzymes involved in photosynthesis and oxygen species detoxification (Schmidt & Husted, 2019). acts various plant cell compartments needs to be transported chloroplasts mitochondria (He al., 2021). The manganese/calcium (Mn/Ca) efflux transporte...