Head circumference measurements from birth to 7 years, obtained from longitudinal data on children born between 1970 and 1977, are set against those from studies made in the United Kingdom earlier this century. A positive secular trend is shown. The children's heads were significantly larger than those born in the same locality 25 years earlier. Growth charts should be updated, as necessary, wi...

background: ncds are the leading disease burdens in china and the ncds risk factors shifts have accelerated at an unprecedented scale over the past 30 years. the aim of this study was to analysis the natural trajectories of ncds risk factors over the life course. methods: the large-scale longitudinal data from the chns includes nine rounds of surveys between 1989 and 2011. overall, 145913 obser...

CONTEXT Considerable concern has been generated in the lay and medical communities by a theory that increased measles-mumps-rubella (MMR) immunization among young children may be the cause of an apparent marked increase in autism occurrence. OBJECTIVE To determine if a correlation exists in secular trends of MMR immunization coverage among young children and autism occurrence. DESIGN, SETTI...