Mesenchymal stromal cells are present in very low numbers in the bone marrow, necessitating their selective expansion on tissue culture plastic prior to their use in tissue-engineering applications. MSC expansion is laborious, time consuming, unphysiological and not economical, thus calling for automated bioreactor-based strategies. We and others have shown that osteogenic grafts can be culture...

The effect of hygroscopic seeding on warm rain clouds was examined using a hybrid cloud microphysical model combining a Lagrangian Cloud Condensation Nuclei (CCN) activation model, a semi-Lagrangian droplet growth model, and an Eulerian spatial model for advection and sedimentation of droplets. This hybrid cloud microphysical model accurately estimated the effects of CCN on cloud microstructure...

Mechanical hill direct seeding of hybrid rice could be the way to solve the problems of high seeding rates and uneven plant establishment now faced in direct seeded rice; however, it is not clear what the optimum hill seeding density should be for high-yielding hybrid rice in the single-season rice production system. Experiments were conducted in 2010 and 2011 to determine the effects of hill s...

Recent interest by producers, researchers, and industry personnel concerning the use of grain drills utilizing 7-in. versus 10-in. row spacing have raised questions as to the optimal drill-row spacing for rice. With the increase in hybrid rice produced and the associated low seeding rates, questions arose regarding the response of these cultivars to row widths. The objective of this study was t...

Abstract To accurately identify ideal operating conditions for scientific cloud seeding and to collect evidence of the effects seeding, a set three flights, with figure‐8‐like paths, was designed supercooled liquid water detection. These flights were conducted near top before during upon re‐entry. Using both in situ aircraft satellite remote sensing observations, comprehensive analysis understa...

Cerebellar pilocytic Astrocytoma is a benign tumor, acounts for 80% of all cerebellar Astrocytoma, and has a relatively good prognosis. This tumor usually presents with Ataxia and in the case of hydrocephaly with raised intracranial pressure signs such as headeach, and vomiting. Treatment of this tumor is complete resection and if hydrocephally is present V.P. shunt should be inserted. In the c...

Protein adsorption is known to direct biological response to biomaterials and is important in determining cellular response in tissue scaffolds. In this study we investigated the effect of the duration of protein adsorption to 3D polymer scaffolds on cell attachment and proliferation. 3D macro-porous polymer scaffolds were pre-aged in serum-containing culture medium for 5 min, 1 d or 7 d prior ...

Most texture-based 3D flow visualization techniques such as volume Line Integral Convolution (LIC) are limited to steady fields. Time-varying dense volume flow visualization is still an open problem due to intensive computation, demanding temporal-spatial coherence, and ad-hoc volume rendering. Our work is based on an enhanced Unsteady Flow LIC (UFLIC) algorithm, Accelerated UFLIC (AUFLIC), whi...

INTRODUCTION Articular cartilage is organized into several zones with differing properties, which as a whole contribute to the overall function of the tissue. These distinct properties arise from zonal differences in chondrocyte phenotype, as previously described [1,2]. To date, however, no studies have addressed zonal variations among single chondrocytes. The goal of this study was to quantify...

There is a clinical need for skin substitutes to replace full-thickness skin loss. Our group has developed a bilayered skin substitute produced from the patient's own fibroblasts and keratinocytes referred to as Self-Assembled Skin Substitute (SASS). After cell isolation and expansion, the current time required to produce SASS is 45 days. We aimed to optimize the manufacturing process to standa...