Five camels and 5 cows were fed with a similar basal diet for six months. They received oral trace element supplementation for 3 months (day 22-112). The supplementation included zinc, copper, selenium, manganese, iodine and cobalt, and corresponded to twice the daily requirement generally recommended for cows. Plasma selenium concentration was significantly lower in the camels (20 ± 2 ng/ml) a...

Twenty pregnant ewes were selected and classified into two groups. The first group received subcutaneous selenium supplementation (0.1 mg of sodium selenite/kg BW) at the 8th and 5th weeks before birth and 1st week after birth while the other was control group without selenium injection. Maternal plasma and serum samples were collected weekly from the 8th week before birth until the 8th week af...

Background: This investigation systematically evaluated the selenium levels and effects of supplementation in patients with autoimmune thyroid disease (AITD).

The European population is only suboptimally supplied with the essential trace element selenium. Such a selenium status is supposed to worsen colitis while colitis-suppressive effects were observed with adequate or supplemented amounts of both organic selenomethionine (SeMet) and inorganic sodium selenite. In order to better understand the effect of these selenocompounds on colitis development ...

Supplementation of selenium has been shown to protect cells against free radical mediated cell damage. The objectives of this study are to examine whether supplementation of selenium stimulates mitochondrial biogenesis signaling pathways and whether selenium enhances mitochondrial functional performance. Murine hippocampal neuronal HT22 cells were treated with sodium selenite for 24 hours. Mito...

The trace element selenium has followed an unusual route on its way to becoming recognized as an essential nutrient. First feared as a plant toxin and later impugned as a suspected carcinogen, it has been shown to be required in the diets of animals and humans, in small quantities, and has been recognized as an effective anticarcinogen. Areas of selenium deficiency have been mapped, worldwide, ...

We report the case of a patient with Crohn's disease receiving short-term postoperative parenteral nutrition supplemented with trace elements who nevertheless became selenium deficient with evidence of a cardiomyopathy. This was fully reversible with oral selenium supplementation. Current parenteral feeding regimes may not contain enough selenium for malnourished patients.

Selenium modifies inflammatory reactions in rodents and humans. The liver controls metabolism and transport of selenium via hepatically-derived SEPP (selenoprotein P). Intracellular SEPS (selenoprotein S) modifies endoplasmic-reticulum function and immune-cell activity. Polymorphisms in SEPS have been associated with cytokine levels and inflammatory diseases in a subset of clinical studies. In ...

INTRODUCTION One of the major causes of mortality in chronic kidney disease (CKD) patients on hemodialysis is premature atherosclerosis. Selenium, a trace element involved in important enzymatic activities inside the body, has protective effects against lipid oxidation and inhibits cholesterol accumulation in blood vessels. OBJECTIVES To determine the effect of selenium supplementation on lip...

Influence of Dietary Supplementation with Organic and Inorganic Selenium Sources on Growth Performance, Carcass Traits Blood Metabolites in Geese Chicken