tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We read with interest the commentary by Drs. Basar and Kahraman (1). The authors provide a comprehensive review of sperm DNA fragmentation (SDF) from etiologies and assisted reproduction outcomes to treatment strategies. We wish to further elaborate the discussion on the use of SDF testing in managing varicocele. Vari...

BACKGROUND Our objective was to use an adapted RT-PCR technique to assess the presence of hepatitis C virus (HCV) in semen and also in different density gradient semen fractions collected from men with chronic viral hepatitis participating in an assisted reproduction programme. METHODS This study included 50 semen samples from 35 HCV(+) men, with active viral replication assessed by RT-PCR, c...

BACKGROUND Evidence on human semen quality as it relates to exposure to various metals, both essential (e.g., zinc, copper) and nonessential (e.g., cadmium, lead), is inconsistent. Most studies to date used small sample sizes and were unable to account for important covariates. OBJECTIVES Our goal in this study was to assess relationships between exposure to multiple metals at environmental l...

A recent review proposed a guideline on the clinical utility of sperm DNA fragmentation (SDF) testing presented by four clinical scenarios in an evidence-based approach (1). This comprehensive review addressed commonly encountered clinical scenarios and provided practice based recommendations. Furthermore, it tried to explain the current indications of SDF testing as well as the management of i...

OBJECTIVE The aim of this study was to determine whether Acridine Orange (AO) can be used as a routine procedure in a physician's office to detect sperm deoxyribonucleic acid (DNA) fragmentation in patients with varicoceles. MATERIAL AND METHODS Forty-five patients with a mean age of 30.4 years, who had been diagnosed with varicoceles by physical examination and 30 healthy males with a mean a...

BACKGROUND Assessment of sperm morphology (including morphometry) is extensively used to determine one of the qualities of a semen sample and depends on the differential staining of spermatozoa. A staining technique should cause as little change to sperm dimensions and form as possible in order to reliably evaluate the morphometric features of the sperm. Various staining techniques have been em...

BACKGROUND Saturated fat intake has been associated with both cardiovascular disease and cancer risk, and a newly published study found an association between saturated fat intake and a lower sperm concentration in infertile men. OBJECTIVE The objective was to examine the association between dietary fat intake and semen quality among 701 young Danish men from the general population. DESIGN ...

Objective: The aim of this study was to evaluate the effects of aging on semen quality in a population of infertile couples. Methods: A cross-sectional study of semen samples obtained from 1,500 men randomly selected from couples who attended an infertility clinic was conducted. The analyses were performed using Spearman’s correlation and Mann-Whitney tests. The age groups consisted of men ≤ 35...

PURPOSE To compare clinical characteristics and surgical results in adolescents and adults with varicocele. MATERIALS AND METHODS We retrospectively analyzed the characteristics of 93 patients, 34 adolescents (mean age, 14.4±2.1 years) and 59 adults (mean age, 30.4±12.4 years), who underwent surgical repair of varicocele between 2006 and 2009. Median follow-up time in all patients was 18.7 mo...

Background: There are several causes leading to male infertility, like oxidative stress, and nutritional deficiency of trace elements i.e., selenium and zinc. The Zinc is the following only to iron as the most abundant element in the body. Although, Zinc is found in red meat, white meat, fish, and milk; the World Health Organization (WHO) approximates that one-third of world population is defic...