Ditte Caroline Andersen,1,2,* Charlotte Harken Jensen,1 and Søren Paludan Sheikh1,3 1Laboratory of Molecular and Cellular Cardiology, Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, 5000 Odense C, Denmark 2Clinical Institute/University of Southern Denmark, 5000 Odense C, Denmark 3Institute of Molecular Medicine/University of Southern Denmark, 5000 Odense C, Den...

Canul-Chay et al. [1] have conducted the segregation experiment of binary granular mixtures in a bed and subjected the bed to vibration. They report that the reverse Brazil-Nut phenomenon (RBNP) was never observed in their experiments and thus conclude that such does not exist. However, we have clearly demonstrated in [2] by Molecular Dynamics simulations that the reverse Brazil-Nut problem not...

In Response to Fakruddin et al. dicted to result in substitutions of amino acids at the and Apostolou et al. corresponding positions in the protein sequence. In each of these cases, individual tumor DNA samples possessed the same sequence as that of the corresponding cell line. We agree with many of the above findings, including To determine if the divergent sequences represented the frequency ...

The floor plate is a group of specialized cells located in the ventral midline of the vertebrate neural tube. It plays important roles in neural tube development as a source of signalling molecules for dorsoventral patterning and axonal guidance (for reviews, see Jessell and Dodd, 1992; Dodd and Jessell, 1993). A floor plate-derived signalling molecule, Sonic hedgehog (Shh), which is a vertebra...

Nightlight Christian Adoptions [3] et al. v. Thompson et al. was a lawsuit filed in the United States District Court for the District of Columbia on 8 March 2001. The suit was filed because Nightlight Christian Adoptions [3], a frozen embryo [4] adoption agency, felt that the Guidelines for Research Using Human Pluripotent Stem Cells [5] published by the National Institutes for Health were unla...

In the last issue, I presented a piece that called into question some of the techniques reported in two papers in high-profile journals that purported to provide statistical evidence for the linguistic status of some ancient symbol systems (Sproat 2010a). Not surprisingly the authors of those two papers took issue with a number of my claims, and have requested the opportunity to respond. The tw...

Thomson [4], et al. v. Thompson, et al. was a lawsuit filed in the United States District Court for the District of Columbia on 8 May 2001 as Civil Action Number 01-CV-0973. This lawsuit was filed in hopes of gaining injunctive relief against a moratorium on the federal funding of stem cell research. The plaintiffs in the case were seven prominent scientists who performed embryonic stem cell re...

The formation of a functioning nervous system requires that axons extend along appropriate pathways to reach correct terminal fields during embryonic development. Axon pathfinding in a broad range of organisms is characterized by the ability of neuronal growth cones to discriminate between appropriate and inappropriate growth substrates (Bovolenta and Mason, 1987; Landmesser et al., 1990; Marcu...

A wedge-shaped anterior hairline extension is a very rare skin manifestation usually associated with congenital anomalies including a Tessier number 10 cleft. Other associated conditions are the Tessier number 9 cleft, the Fraser syndrome, and the Manitoba oculotrichoanal syndrome (MOTA syndrome). The Tessier number 10 cleft features include a coloboma of the middle third of the upper eyelid, a...

Michael Atlan, Michel Gross, Pierre Desbiolles, Émilie Absil, Gilles Tessier, and Mäıté Coppey-Moisan Laboratoire Kastler-Brossel de l’École Normale Supérieure, CNRS UMR 8552, Université Pierre et Marie Curie Paris 6, 24 rue Lhomond 75231 Paris cedex 05. France École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris, CNRS UPR 5, Université Pierre et Marie Curie Paris 6, 10 ...