A reference table is presented for rapid determination of 50% lethal doses or 50% infective doses after administering 10-fold serial dilutions of toxins, viruses, sera, etc., to six animals per dilution.

Herein, CoF2 nanoparticles (NPs) are prepared by simple coprecipitation method and characterized various techniques, i.e., XRD, SEM/EDX, FTIR, UV/Vis, for their structure identification. As-prepared nanostructures were used as photocatalyst, antioxidant, antimicrobial agent. The degradation studies of the samples carried out specific time methylene blue (MLB) dye under a UV/visible spectrophoto...

Our study performed upon an extended series of 28 compounds of 1,2,4-triazole derivatives that demonstrate substantial in vitro antimicrobial activities by serial plate dilution method, using quantitative structure-activity relationship (QSAR) methods that imply analysis of correlations and multiple linear regression (MLR); a significant collection of molecular descriptors was used e.g., Edge a...

AIMS To determine the sensitivity of commercially available diagnostic assays for Chlamydia trachomatis using a simple method. METHODS Nine commercial assays and an "in-house" polymerase chain reaction (PCR) were evaluated using serial dilutions of a laboratory grown H serovar--four of them using a laboratory grown E serovar. Seven of the assays were further tested using dilutions of several ...

Immunoreactive methionine enkephalin and beta-endorphin were sought by serial dilution of tissue extracts and assay of chromatographic fractions in non-endocrine tumour tissue from three patients with the ectopic adrenocorticotrophin syndrome associated with carcinoid tumours and in normal lung tissue and thymic tissue from a patient with myasthenia gravis. In all cases serial dilution of extra...

BACKGROUND & OBJECTIVES Leptospirosis, a zoonosis with a worldwide distribution is an acute febrile illness caused by spirochaetes of the pathogenic Leptospira interrogans. Microscopic agglutination test (MAT), the reference method for diagnosis was successively done to evaluate the modified ELISA which was developed with the recombinant LipL32 antigen for the detection of anti-leptospiral anti...

A commercially available instrument that automatically makes serial dilutions and delivers reagents was used for the determination of antistreptolysin O titers in serum. The automated method was compared with tube-dilution and manual microtitration techniques. It gave higher reproducibility of results and was quicker to perform than both the other tests; and it was much more economical in reage...

New 3-substituted 1-(3-hydroxyphenyl)-5-oxopyrrolidine derivatives containing hydrazone, azole, diazole, oxadiazole fragments, as well as 2-phenoxy- and 2,3-diphenoxy-1,4-naphthoquinone derivatives were synthesized. The structure of all compounds has been confirmed by NMR, IR, mass spectra, and elemental analysis data. Methyl 1-{3-[(3-chloro-1,4-dioxo-1,4-dihydro-2-naphthalenyl)oxy]phenyl}-5-ox...

Among the 5-membered nitrogen heterocycles, the privileged scaffolds thiazole and 1,3,4-oxadiazole have been incorporated in a single molecular framework to explore new potential antimicrobial agents. The newly synthesized compounds 5a-l have been synthesized and characterized by IR, H and C NMR spectroscopy and mass spectrometry. The structures of the synthesized compounds are in full agreemen...