kernicterus (bilirubin induced encephalopathy) is an uncommon disorder with tragic consequences, especially when it affects healthy term and near-term neonates. appointment of cut off value of total serum bilirubin level that have a safe margin for early prompt treatment, as a result, prevention of kernicterus. in our study, all of icteric neonates that admitted in our center in 1 year were enr...

antidiabetic action of garlic is established in animal studies. since all of the pervious studies have focused on the therapeutic role of garlic, this study investigated the preventive effect of garlic juice on biochemical factors and histological features in streptozotocin (stz)-induced diabetic rats. forty male rats were divided into five groups (n = 8): 1-normal group (n), 2-normal+garlic gr...

due to a narrow therapeutic range, measurment of theophylline serum levels is highly recommended in patients with a long-term theophylline therapy. in this regard, since blood sampling is an invasive method, exploring alternative methods using other biological fluids in particular saliva samples are targeted. this study was designed to determine any relationship between serum and saliva levels ...

background and objectives: the magnetotactic bacterium magnetospirillum gryphiswaldense (msr-1) mineralizes the magnetite (fe3 o4) crystals and organizes a highly ordered intracellular structure, called the magnetosome. iron transport system supports the biogenesis of magnetite. although iron is an essential trace element for many metabolic pathways of the body, increase or decrease in iron wil...

background: exposure to heavy metals in development of many diseases has been investigated previously, specially created by oxidative stress. the etiology of rheumatoid arthritis (ra) is still not fully understood but oxidative stress created by heavy metals may have role in development of ra. the aim of present study was to compare serum level of heavy metals in ra and healthy control individu...

body mass index (bmi) has been demonstrated to be associated with serum uric acid (sua) level in many developed countries, however, there is still a lack of large sample study in jiangsu province, one of the most economically developed regions in china, where fat-rich diet is common.through retrospective analysis in healthy subjects, we determined the association of bmi with hyperuricemia risk....

multiple sclerosis (ms) is an inflammatory demyelinating disease which the exact etiology is still are far to be clear. reasons for this autoimmune disease are unknown origin. the aim of present study was to evaluate serum levels of selenium in patient with ms compare to healthy subjects. a total of 46 subjects were enrolled in the study, sera of 23 ms cases and 23 healthy normal cohorts as con...

background: obesity is caused by several factors while sedentary lifestyle and excessive energy intake are the most important ones. obesity could be due to abnormal calcium metabolism, and a high calcium intake may prevent obesity. studying serum calcium level, albumin, and triglyceride concentrations, we searched for probable correlation between serum calcium level and anthropometric data of t...

background: oocyte maturation and subsequent in vitro production (ivp) of embryos are affected by diverse groups of chemicals in maturation medium which are needed for successful mammalian oocyte maturation during which the dramatic cytoplasmic and nuclear reprogramming events take place. this study was designed to evaluate the effects of protein source (fetal bovine serum, fbs, and bovine seru...

background: pregnancy and accelerated fetal growth always are related with major metabolic changes and body fat redistribution and adiponectin is one of principle adipocyte hormones, so studying adiponectin changes during pregnancy may reveal some hidden parts of fetal metabolism. the aim of this study was to assess adiponectin and leptin levels in umbili cal cord and maternal serum, their rela...