نتایج جستجو برای: serum amyloid
تعداد نتایج: 338050 فیلتر نتایج به سال:
Backgrounds The available literature on the correlation between serum amyloid A (SAA) and prognosis of chronic kidney disease (CKD) are limited, findings from existing studies inconclusive. This meta-analysis aimed to evaluate evidence regarding link SAA risks all-cause cardiovascular mortality in CKD patients. Additionally, we investigate potential dose-response relationships, provided that ad...
A 68-year-old Afro-Caribbean woman presented with shortness of breath. Past history included bilateral carpal tunnel syndrome. Her father had died in his mid-40s, from heart failure. The patient was hypertensive (148/103mmHg) with mild peripheral oedema. An electrocardiogram showed atrial flutter at 160 beats/min, with low-normal limb lead voltage, and pre-cordial Q-waves (pseudo-infarction pat...
Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly secreted by hepatocytes. However, its role in liver injury and fibrogenesis has not been elucidated so far. In this study, we determined the effects of SAA on hepatic stellate cells (HSCs), the main fibrogenic cell type of the liver. Serum amyloid A potently activated IκB kinase, c-Jun N-terminal...
Amyloid protein AA is the presumptive fragment of an acute phase serum apolipoprotein, apoSAA. Two major murine apoSAA isotypes (apoSAA1 and apoSAA2) have been identified. The NH2-terminal amino acid sequences of purified murine apoSAA1 and apoSAA2 have been examined and compared with that of murine amyloid protein AA. Our results indicate that apoSAA1 and apoSAA2 are separate gene products and...
Serum amyloid protein A (SAA), the precursor of secondary amyloid protein, is elevated in chronic diseases which are associated with an increased incidence of amyloid. However, SAA is also elevated in acute bacterial and viral infections and somes forms of cancer. The murine model of casein-induced amyloidosis was studied to determine the relationship between SAA production and amyloid depositi...
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