To the Editor: Nowadays, there is growing interest in the possible relationship between selenium metabolism and the aging process [1 ]. Epidemiological studies show that selenium may have a preventive role in some degenerative diseases such as hepatic cirrhosis, cardiovascular diseases, and some types of cancer [2, 3 ]. However, information on the influence of selenium on aging is contradictory...

OBJECTIVE To estimate serum zinc and selenium levels in a group of healthy subjects and correlate these with epileptic patients. METHODS This case-control study was conducted in the Department of Neurology, Valiasr Hospital, Iran, between November 2011 and May 2012 on 40 patients aged 26.63+/-5.78 years who were diagnosed with generalized and a single epileptic form of epilepsy by a neurologi...

Twenty pregnant ewes were selected and classified into two groups. The first group received subcutaneous selenium supplementation (0.1 mg of sodium selenite/kg BW) at the 8th and 5th weeks before birth and 1st week after birth while the other was control group without selenium injection. Maternal plasma and serum samples were collected weekly from the 8th week before birth until the 8th week af...

Selenium food fortification could be a cost-effective strategy to counteract the inadequacy of selenium intake among the Italian population. In this study, the effect of foliar fertilization with sodium selenate of an Italian rice cultivar and the increase of serum selenium and of erythrocyte glutathione peroxidase (GPx) activity after intake of fortified rice, have been evaluated. The effect o...

An experiment was conducted to evaluate the effects of high dietary levels of selenium (as sodium selenite) and copper (as copper sulphate) on growth performance, serum biochemical parameters and antibody production against Newcastle disease vaccine (NDV) virus in broiler chickens. A total of 160 Ross 308 unsexed day old broiler chickens were randomly allocated into four treatment groups (n=40 ...

BACKGROUND Selenium is needed by all living cells in order to ensure the optimal function of several enzyme systems. However, the selenium content in the soil in Europe is generally low. Previous reports indicate that a dietary supplement of selenium could reduce cardiovascular disease but mainly in populations in low selenium areas. The objective of this secondary analysis of a previous random...

Abnormal regulation of local vascular tone occurs early in human and experimental atherosclerosis. Impaired endothelium-dependent vascular relaxations mediated by endothelium-derived relaxing factor are an important contributor to these abnormalities. Endothelium-derived relaxing factor is nitric oxide released as such or attached to a carrier molecule. Oxidized lipoproteins impede endothelium-...

background: vanadium is an important environmental and industrial pollutant. it has a status of reproductive toxicant and is reported to cross placental barrier. objective: the current study was performed to assess the therapeutic efficacy of tiron and its combination with selenium against vanadium induced toxicity in lactating and suckling rats. materials and methods: rats were exposed to vana...

In rats, the respective contribution of the thyroid and peripheral tissues to the pool of T3 remains unclear. Most, if not all, of the circulating T3 produced by extrathyroidal sources is generated by 5'-deiodination of T4, catalyzed by the selenoenzyme, type I iodothyronine 5'-deiodinase (5'D-I). 5'D-I in the liver and kidney is almost completely lost in selenium deficiency, resulting in a mar...