The role of gonadotropins, androgens, and insulin in the regulation of circulating leptin levels is obscure. In order to clarify the relationships of these parameters we studied serum leptin levels in 19 healthy control subjects and in 35 hyperandrogenic and hyperinsulinemic patients with polycystic ovary syndrome (PCOS). Serum leptin concentrations did not differ significantly between PCOS pat...

Dyslipidemia in cancer patients is reported to be linked with cancer risk and progression of the disease. Previous research findings showed that low levels of serum cholesterol and elevated levels of serum triglycerides are associated with risk of overall cancers. However, there are several inconsistencies in the reports regarding the association of dyslipidemia with cancers. In this book chapt...

Serum triglyceride levels were significantly raised in 37 markedly obese females, especially in the younger subjects; cholesterol and phospholipid levels were normal. Considerable variation in triglyceride levels of equally obese subjects was observed. No relationship was noted between triglyceride levels and the pattern of subcutaneous fat distribution. It is suggested that the high triglyceri...

dialyser membrane would continuously flex as samples of different protein concentrations are analysed the peak height of a specimen does not necessarily reflect its creatinine level. In the authors' experience this produces many bizarre peak shapes within every batch and the last peak is always higher than expected. One way of minimising conformational changes in the dialyser membrane is to rai...

We describe a modified method for determining triglycerides in serum, in which alumina is used to adsorb interfering substances, and the glycerol content of triglycerides is determined colorimetrically. In contrast to all previous Hantzsch condensation procedures in which periodate and acetylacetone are used, the working periodate and the working acetylacetone reagents are stable for at least s...

The aims of this study were to investigate the validity of Friedewald's formula and to propose a range of triglyceride values over which the formula can be used without significant error. This was a cross-sectional analysis of 1,929 subjects (946 males and 983 females) aged 20 yr and older using data of the Korea National Health and Nutrition Examination Survey in 2009. Estimated total number w...

This rapid, simplified assay for serum triglycerides is based on the use of a more effective solvent extraction procedure, ethoxide transesterification, and color development with acetylacetone. No phospholipid adsorption step is necessary. The procedure requires less than 0.2 ml of serum, no expensive or elaborate apparatus, and 5 to 10 values can be obtained per hour, with better precision th...

We report a new kinetic approach to the quantification of triglycerides (triacylglycerols) in human sera. The new approach combines a commercially available enzyme-reagent system with a multiple-linear-regression data-processing method. Values of absorbance collected at 3-s intervals between 20 and 305 s are fitted to a pseudo-first-order model to compute the total change in absorbance expected...