نتایج جستجو برای: serum uric acid
تعداد نتایج: 1010352 فیلتر نتایج به سال:
OBJECTIVE Various commonly consumed foods have long been suspected of affecting the serum uric acid level, but few data are available to support or refute this impression. Our objective was to evaluate the relationship between dietary factors and serum uric acid levels in a nationally representative sample of men and women in the US. METHODS Using data from 14,809 participants (6,932 men and ...
BACKGROUND Hyperuricaemia has long been known to be associated with cardiovascular disease, and it is particularly common in patients with kidney disease, metabolic syndrome and diabetes mellitus. Metabolic syndrome is associated with pro-inflammatory and prothrombotic state. AIM To examine the association between renal function, serum uric acid and markers of both pro-inflammatory and prothr...
AIM To determine whether fasting serum uric acid is associated with the insulin sensitivity index or with other anthropometric, metabolic or environmental features of the insulin resistance syndrome in a population-based sample of young healthy Caucasians. METHODS The protocol included 380 unrelated Caucasian subjects (age 18-32 years) who had their insulin sensitivity index and glucose effec...
OBJECTIVE To examine the effects of fenofibrate, an antilipotropic drug, on uric acid metabolism in healthy male subjects and on urate transporter 1 (URAT1). METHODS Fenofibrate was administered to nine male volunteers at a dose of 300 mg (corresponding to 200 mg of micronized fenofibrate), and the metabolic parameters of uric acid were investigated for more than 12 hours. In addition, the ef...
High serum uric acid levels elevate pro-inflammatory-state gout crystal arthropathy and place individuals at high risk for cardiovascular morbidity and mortality. Genome-wide scans in the genetically isolated Sardinian population identified variants associated with serum uric acid levels as a quantitative trait. They mapped within GLUT9, a Chromosome 4 glucose transporter gene predominantly exp...
in this study, incorporation of iron ion-doped natrolite nanozeolite, multi-wall carbon nanotubes into chitosan-coated glassy carbon electrode for the simultaneous determination of ascorbic acid, epinephrine, uric acid and tyrosine is studied. the results show that the combination of multi-wall carbon nanotubes and iron ion-doped natrolite zeolite causes a dramatic enhancement in the sensitivit...
Sleep disordered breathing as well as high serum uric acid levels are independent risk factors for cardiovascular disease. However, studies evaluating the relationship between sleep-disordered breathing and hyperuricemia are limited. We examined the 2005-2008 National Health and Nutrition Examination survey's sleep variables and high serum uric acid among 6491 participants aged ≥20 years. The s...
BACKGROUND/OBJECTIVES Metabolic syndrome (MetS) is a set of interrelated metabolic risk factors that increase the risk of cardiovascular morbidity and mortality. Studies regarding the specificity and sensitivity of serum levels of leptin and uric acid as predictors of MetS are limited. The aim of this study was to evaluate the serum levels of leptin and uric acid in terms of their specificity a...
INTRODUCTION Uric acid is the most abundant molecule with antioxidant properties found in human blood serum. We examined the relationship between serum uric acid and the incidence of respiratory disease including any effect modification by smoking status. METHODS A cohort with serum uric acid measured between 1 January 2000 and 31 December 2012 was extracted from The Health Improvement Networ...
Objective: This study examined the association of homocysteine and uric acid with estimated glomerular filtration rate (eGFR) and explored their pathophysiological significance in patients with type 2 diabetes mellitus. Methods: We performed a cross-sectional study in 56 Japanese patients with type 2 diabetes. The correlations of serum total homocysteine level with age, diabetes duration, HbA1c...
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