Background and Aims: Percutaneous coronary interventions have been provided in various hospitals of Nepal for more than two decades. Hence, we aimed to study the percutaneous intervention revascularization status patients with artery disease at a tertiary center eastern Nepal.
 Methods: A cross sectional was conducted Birat Medical College Teaching Hospital from 1st Aug 30th Feb 2023. Nine...

We were very interested to read the article dealing with therapeutic options in patients with chronic refractory angina pectoris (RAP) signed by Cohen et al. 1 The authors presented an excellent review of the therapeutic options for such ''no-option'' patients suffering from chronic RAP caused by severe symptomatic and chronic coronary artery disease. May we quote Dr. Cohen and colleagues: ''Re...

In the United States, there are about 17.6 million patients suffer from symptomatic coronary artery disease (CAD), affecting 7.9% of adults ≥ 20 years of age.1 An estimated 10.2 million patients have angina, and 500,000 patients will develop new angina pectoris each year.1 A subset of angina patients are categorized as refractory when symptoms continue despite optimal medical therapy and revasc...

BACKGROUND Vascular endothelial growth factor (VEGF) induces mobilization of endothelial progenitor cells (EPCs) with the capacity for proliferation and differentiation into mature endothelial cells, thus contributing to the angiogenic process. OBJECTIVE We sought to assess the behavior of EPCs in patients with ischemic heart disease and refractory angina who received an intramyocardial injec...

OBJECTIVES We sought to verify whether the intravascular metabolism of chylomicron-like emulsion may predict the clinical evolution of patients with coronary artery disease (CAD) undergoing secondary prevention therapy of CAD. BACKGROUND Case-control studies have suggested an association between impaired intravascular catabolism of triglyceride (TG)-rich lipoproteins and CAD. However, evidenc...

BACKGROUND There are a growing number of patients with end-stage coronary artery disease (CAD) and refractory angina. Angiogenesis may be induced by intramyocardial injection of autologous bone marrow stem cells, intensified by inflammation around channels performed by laser. AIM To assess the effect of a combined treatment consisting of transmyocardial laser revascularisation (TLMR) and intr...

Alongside the remarkable advances in medical and invasive therapies for the treatment of ischemic heart disease, an increasing number of patients with advanced coronary artery disease unsuitable for revascularization continue to suffer from angina pectoris despite optimal medical therapy. Patients with chronic angina have poor quality of life and increased levels of anxiety and depression. A co...

Despite sophisticated conventional medical treatment and the continued development and improvement of coronary revascularization modalities in recent years, a significant number of patients still suffer from refractory angina pectoris and cannot be successfully managed. Advances in therapeutic options have led to an increase in the average of life expectancy even in such no-option patients. Man...

OBJECTIVES Paresthesia-free stimulation such as high frequency and burst have been demonstrated as effective therapies for neuropathic pain. The aim of this meta-analysis was to evaluate the efficacy and safety of conventional spinal cord stimulation (SCS) in the treatment of refractory angina pectoris (RAP). MATERIALS AND METHODS Relevant randomized controlled trials that investigated SCS fo...