AIM Evaluation of the diagnostic contribution of color duplex sonography of the temporal, carotid and vertebral arteries and doppler sonography of the periorbital arteries in patients with and without giant cell arteries (GCA) particularly to distinguish between arteritic and nonarteritic neuro-ophthalmological vascular complications (NOC). METHODS In a prospective study ultrasonographic find...

OBJECTIVE Aberrant rho kinase (ROCK) activity is implicated in the pathogenesis of several vascular diseases and is associated with Th17 differentiation. Th17 immune response is recognized in the pathogenesis of GCA. The aim of this study was to assess ROCK activity in GCA. METHODS All patients who underwent temporal artery biopsy (TAB) at a tertiary care centre over 5 years were identified a...

PURPOSE OF REVIEW Giant cell arteritis (GCA) is a serious disease and the most common cause of vasculitis in the elderly. Here, studies describing the recent discovery of varicella zoster virus (VZV) in the temporal arteries of patients with GCA are reviewed. RECENT FINDINGS GCA is characterized by severe headache/head pain and scalp tenderness. Many patients also have a history of vision los...

Guanylyl cyclase A (GCA) and soluble guanylyl cyclase (sGC) encode GCs in Dictyostelium and have a topology similar to 12-transmembrane and soluble adenylyl cyclase, respectively. We demonstrate that all detectable GC activity is lost in a cell line in which both genes have been inactivated. Cell lines with one gene inactivated were used to characterize the other guanylyl cyclase (i.e. GCA in s...

PURPOSE In patients with suspected giant cell arteritis (GCA), a search for the perivascular halo sign, a sophisticated color duplex ultrasound (CDU) finding, at experienced centers reliably identifies inflamed temporal arteries (TA). We tested whether TA compression in patients with GCA, a simple, largely operator-independent maneuver, elicits contrasting echogenicity between the diseased arte...

Artificial selection of high yield crops and better livestock is paramount importance in breeding programs. Selection of elite parents with preferred traits from a phalanx of inbred lines is extremely laborious, time-consuming and highly random. General combining ability (GCA) was proposed and has been widely used for the evaluation of parents in hybrid breeding for more than half a century. Ho...

OBJECTIVE Results of previous studies investigating the association between GCA and malignancy are conflicting. We performed a study of the risk of cancer in patients with biopsy-proven GCA. METHODS Patients with biopsy-proven GCA were identified from pathology reports of temporal artery biopsies from the major pathology laboratories in South Australia (SA). All subjects with biopsy-proven GC...

Gastric cardia adenocarcinoma (GCA) is the most aggressive subtype of gastric cancer with a high metastatic rate. In this report, we collected tumor tissue samples from 214 GCA cases and examined expression of CYR61, a target gene product of the Hippo-YAP/TAZ pathway, in the GCA tumors by immunohistochemical (IHC) staining using the tissue microarray assay (TMA). The results have shown that CYR...

OBJECTIVES To determine the following: (1) the proportion of babies reclassified as small or appropriately grown using customized and population centiles; and (2) the relative risks of perinatal morbidity, including abnormal umbilical Doppler studies, in babies classified as small for gestational age (SGA) and appropriate for gestational age (non-SGA) using the two centile calculations. DESIG...

ةصلاخلا Allopeas gracilis is recorded for the first time in southern Iraq. It was collected from two localities (Abu-Al Khaseeb region and Hareer region) from Basrah city. ضرلاا عقوقلا نم ةنيع نورشعو نامث ي Allopeas gracilis مت للاخ ةرصبلا ةنيدم ،ريرح ةقطنم و بيصخلا وبا ةقطنم نم اھعمج ناسين رھش 2008 راذاو 2008 يلاوتلا ىلع . ليجستلا اذھ ربتعي دعب ةرصبلا ةنيدم نم ةيضرلاا عقاوقلا نم ثلاثلا Monacha...