Endothelial cells (ECs) that line the inner surface of blood vessels are continuously exposed to fluid frictional force (shear stress) induced by blood flow, and shear stress affects the intracellular calcium ([Ca2+]i), which initiates cellular responses. Here, we studied the effect of long-term exposure of shear stress on [Ca2+]i responses in cultured ECs by using a confocal laser microscope a...

Title of dissertation: HIGH STRENGTH SEMI-ACTIVE ENERGY ABSORBERS USING SHEARAND MIXED-MODE OPERATION AT HIGH SHEAR RATES Andrew Craig Becnel Doctor of Philosophy, 2014 Dissertation directed by: Professor Norman M. Wereley Department of Aerospace Engineering This body of research expands the design space of semi-active energy absorbers for shock isolation and crash safety by investigating and c...

BACKGROUND This study describes a new method for determining site-specific vascular shear stress using dynamic measures of shear rate and blood viscosity (BV) in the carotid arteries, and examines characteristics of carotid arterial shear stress among patients with lacunar infarction. METHODS Vascular shear stress measurements were conducted in 37 patients (17 lacunar infarction patients and ...

The Enskog kinetic theory for moderately dense gas-solid suspensions under simple shear flow is considered as a model to analyze the rheological properties of the system. The influence of the environmental fluid on solid particles is modeled via a viscous drag force plus a stochastic Langevin-like term. The Enskog equation is solved by means of two independent but complementary routes: (i) Grad...

in this paper a laboratory study has been carried out on the effect of changing the type of soil filling cylindrical reinforcing elements from sm to gm on behavior of sandy soil. in this study the primary tests for evaluation of the impact of reinforced sand and gravel columns with diameters of 5 cm and heights of 15 cm subjected to vertical stresses of 50, 100, and 150 kpa were carried out in ...

Significant differences between epicardial and endocardial systolic stress in the wall of the left ventricle (LV) have been predicted by various models of LV mechanics. Yet a model incorporating transmural differences in fiber orientation and torsion, defined as a rotation of the apex with respect to the base around the long axis of the LV, predicts transmural equalization of stress and shorten...

We study a simple scalar constitutive equation for a shear-thickening material at zero Reynolds number, in which the shear stress sigma is driven at a constant shear rate gamma; and relaxes by two parallel decay processes: a nonlinear decay at a nonmonotonic rate R(sigma(1)) and a linear decay at rate lambda sigma(2). Here sigma(1,2)(t)= tau(-1)(1,2) integral (t)(0)sigma(t')exp[-(t-t')/tau(1,2)...

The predominant mode of distress for unbound pavement layers is the permanent deformation of the layer either through gradual deformation or rapid shear failure of the layer. Several researchers have related both these forms of permanent deformation to the ratio of the imposed stress over the shear strength of the material. Conventionally, the shear strength of the material was characterised wi...

This paper develops a new approach to computing the shear rate from the torque and rotationalvelocity measurements in a Couette rheometer. It is based on wavelet-vaguelette decomposition sWVDd proposed by Donoho fDonoho, D., Appl. Comput. Harmon. Anal. 2, 101–126 s1995dg. This decomposition consists in expanding the shear rate into a truncated wavelet series, whose coefficients can be determine...