BACKGROUND Although it is well known that aspirin causes gastroduodenal mucosal injury and that aspirin-induced gastroduodenal mucosal injury is often asymptomatic, the prevalence and independent factors for gastroduodenal mucosal injury have not been clarified in asymptomatic patients taking low-dose aspirin and gastroprotective agents. AIM To clarify the prevalence and independent factors f...

ptk (phototherapeutic keratectomy) is the use of laser in corneal diseases. we can replace ptk for many other invasive procedures. the objective of this study is the assessment of this procedure in several cases in our practice. this investigation was a retrospective study, which was conducted based on comparison of 11 eyes with corneal eschars, induced by recurrent corneal erosions, pterygium ...

BACKGROUND The aim was to determine the accuracy of high-resolution ultrasonography (US) for detecting erosion in the metacarpophalangeal (MCP) and wrist joints of patients with different subtypes of systemic lupus erythematosus (SLE) arthritis, using computed tomography (CT) as the gold-standard reference method. METHOD The ulnar head, radiocarpal and second to fifth MCP joints in 26 patient...

OBJECTIVE To determine whether the presence of radiographic erosions at disease onset in patients with early rheumatoid arthritis (RA) is associated with clinical, serological, or genetic factors of poor outcome and whether patients with erosions only in the feet have a different pattern of presentation. METHODS Sixty one patients with early RA (<6 months of evolution) were studied. Clinical ...

OBJECTIVE Anti-cyclic citrullinated peptide (anti-CCP) antibodies are a stronger predictor of the severity of rheumatoid arthritis than is rheumatoid factor (RF). Their role in predicting outcome in unselected patients with new-onset inflammatory polyarthritis (IP) has not been examined. The aims of this study were to examine the role of baseline RF and anti-CCP antibodies in determining the li...

The association of pemphigus and thymoma is real, although rare. We report a 73-year-old woman presenting with cutaneous bullac and erosions superimposed on erythematous and urticarial plaques, and a positive Nikolsky sign. She. had a large mediastinal mass that proved to be a benign thymoma. Her skin biopsy and direct immunofluorescence test were suggestive of superficial pemphigus.