Growing interest to use natural preservatives and spices with antimicrobial effects and large amounts of floral bio-residues (92.6 g per 100 g) generated and wasted in the production of saffron spice guided this study  to evaluate  the opportunity to expand the uses of C. sativus flowers (petals and stamens), beyond the spice (dried stigmas). The antibacterial potential of total extrac...

This study was conducted to determine frequency and pattern of antimicrobial susceptibility of Shigella species isolated from stool specimens collected from patients presenting with bloody diarrhoea in Mwanza City, Tanzania. The study was carried out from October 2004 to October 2005 and involved patients attending Sekou Toure Regional Hospital and Butimba Health Centre. Bacteriological culture...

We examined a virulent strain of Shigella dysenteriae type 1 after induction into the viable but nonculturable (VBNC) state for its ability to (i) maintain the Shiga toxin (stx) gene; (ii) maintain biologically active Shiga toxin (ShT); and (iii) adhere to intestinal epithelial cells (Henle 407 cell line). PCR was used to amplify the stx gene from VBNC cells of S. dysenteriae type 1, thereby es...

The nanomaterials have important application in different field of science such as biology and pharmacology, which draws the attention of biologists towards this field of study more than before. As the worldwide mortality rate is high due to the pathogens and especially because of the bacteria associated dysenteriae and the antibacterial effect of metal nanoparticles is well known from centurie...

shigella species (spp.) are gram-negative bacteria that are responsible for shigellosis. although it can be controlled via antibiotics, increasing number of antibiotic resistant isolates of shigella have been reported. therefore, other strategies such as production of specific vaccine against this organism could be a suitable therapeutic approach. attenuated live vaccines produced by gene delet...

In a previous communication (Mackie, 1938) we have reported observations upon the Shigella dysenteriae agglutinin curves in a group of patients presenting the intestinal pathology of chronic bacillary dysentery and bacteriologic or serologic evdence of infection by these organisms. Fluctuation of the titre curves in individual patients, the common finding of higher titres in the culture-negativ...