Flavonoid compound was isolated from Crinum amabile Donn. leaves. The separation of flavonoids carried out by using chromatographic techniques to purify CH2Cl2 extract Column chromatography with silica gel and sephadex as stationary phases, thin-layer chromatography, preparative were the used in this research. pure obtained form white-yellow solid Rf value is 0.44. Compound identification 1H-NM...

Lamellar nanocomposites based on semiconducting polymers incorporated into layered inorganic matrices are prepared by the co-assembly of organic and inorganic precursors. Semiconducting polymer-incorporated silica is prepared by introducing the semiconducting polymers into a tetrahydrofuran (THF)/water homogeneous sol solution containing silica precursor species and a surface-active agent. Semi...

Efficient and selective conversion of renewable feedstocks to essential chemicals fuels applying green sustainable catalytic processes is central importance attracts scientific interest. Among different biomass-based feedstocks, 5-hydroxymethylfurfural (HMF) represents valuable platform compound widely used for the synthesis chemicals, fuels, polymers. Here we report cobalt nanoparticles cataly...

Captive giraffe (Giraffa camelopardalis) mostly do not attain the longevity possible for this species and frequently have problems associated with low energy intake and fat storage mobilization. Abnormal tooth wear has been among the causes suggested as an underlying problem. This study utilizes a tooth wear scoring method ("mesowear") primarily used in paleobiology. This scoring method was app...

Magnolol (MG) is a small-molecule neolignan polyphenolic compound isolated from the genus Magnolia. The anti-inflammatory, anti-oxidative, anti-diabetic, anti-tumorgenic, anti-neurodegenerative, anti-depressant and anti-microbial properties of MG are well documented in recent literature. These fascinating multiple biological activities of MG encourage research about the development of new deliv...

Salvia genus, which is generally called Maryam-Goli in the Persian language, belongs to Lamiaceae family and comprises 58 species in Iran. Four flavonoids plus a steroid compound were isolated from the ethyl acetate and methanol extracts of the aerial parts of Salvia macrosiphon Boiss, using different chromatographic methods on the silica gel and sephadex LH20. The structures of the isolated co...

the tumors in which odontogenic differentiation is fully expressed are the odontomas. odontomas are considered as hamartomas rather than a true neoplasm. these tumors are composed of enamel, dentine, cementum and pulp tissue. it is most commonly associated with the eruption of the teeth. they are usually discovered on routine radiographic examination. in exceptional cases, the odontoma erupts i...

A new compound, migrastatin, was isolated from a cultured broth of Streptomyces sp. MK929-43F1, as an inhibitor of tumor cell migration. It was purified by column chromatographies on silica gel and Sephadex LH-20 and HPLC. Migrastatin has the molecular formula of C27H39NO7 consisting of 14-membered macrolide and glutarimide moiety. It inhibited spontaneous migration of human esophageal cancer E...

Virtual screening (VS) approaches have been constantly increasing their applications into hit discovery process. In the last few years, we have perfonned an intensive screening campaign using different in silica strategies and combining them with a biochemistry validation. In the present work, using a consensus docking approach, we have identified a small family of novel protein kinase A (PKA) ...