OBJECTIVES The aim of this study was to measure tear film surface quality (TFSQ) using dynamic high-speed videokeratoscopy during short-term (8 hrs) use of rigid and soft contact lenses. METHODS A group of 14 subjects wore 3 different types of contact lenses on 3 different nonconsecutive days (order randomized) in 1 eye only. The subjects were screened to exclude those with dry eye. The lense...

PURPOSE This study aimed to examine the effects of demographic, lens performance, and ocular surface response measures on contact lens-related discomfort and dryness, using a large contact lens study database. METHODS A total of 4164 records were extracted from a database of 220 subjects participating in 46 silicone hydrogel contact lens studies. Subjects discontinued lens wear for 24 hours a...

PURPOSE The aim of this study was to quantify specific proteins deposited on daily wear silicone hydrogel lenses used in combination with multipurpose disinfecting solutions (MPDSs) by applying multiple-reaction-monitoring mass spectrometry (MRM-MS). METHODS Balafilcon A or senofilcon A contact lenses used with different MPDSs on a daily wear schedule were collected. Each worn lens was extrac...

Corneal changes were monitored in 14 subjects following 3 hr of eye closure while wearing selected oxygen permeable rigid and hydrogel lenses. The mean increase in corneal thickness ranged from 82.5 to 29.5 microns for rigid lenses with oxygen transmissibilities (Dk/L) between 0.2 X 10(-9) and 57.0 X 10(-9) (cm/sec) (ml O2/ml X mmHg), respectively, and ranged from 82.5 to 23.5 microns for hydro...

dry eye is the major contributor to computer vision syndrome. the reductions in the blink rate and amplitude have been considered as the possible mechanisms leading to this condition. the purpose of this study is to evaluate the changes in the lower tear meniscus heights and areas in the computer reading task, in dry eye subjects, with and without soft contact lenses. in this quasi-experimental...

Corneal thickness changes were monitored in ten subjects (1) over a 36-hour period without contact lens wear and (2) during 7 days continuous wear of three types of hydrogel contact lenses of different back vertex powers. Measured on awakening, the mean overnight central corneal edema without lenses was 3.0% ± 1.2%. With the lenses used in this study, the mean overnight corneal swelling over th...

PURPOSE Many soft contact lens wearers have symptoms or signs that compromise successful lens wear. This study estimated the prevalence of problems in current wearers of soft contact lenses and tested the effect of refitting patients with senofilcon A silicone hydrogel lenses (ACUVUE Oasys). METHODS Prevalence was estimated from 1,092 current lens wearers for frequent or constant discomfort o...

Microbial keratitis (MK) is the most visually devastating complication associated with contact lens wear. Pseudomonas aeruginosa (PA) is highly invasive in the corneal epithelium and is responsible for more than half of the reported cases of contact lens-related MK. To protect against Pseudomonas-mediated MK, the corneal epithelium has evolved overlapping defense mechanisms that function to pro...

AIM To observe the curative effect of bandage contact lens in neurogenic keratitis. METHODS Twenty cases of neurogenic keratitis were studied at the Department of Ophthalmology, the first Affiliated Hospital of China Medical University, between October 2012 and June 2013. These included 13 males and 7 females, aged from 35 to 88y. Patients were voluntarily divided into an experimental group (...

background: poor hygiene will provide good condition for corneal infections by opportunistic free-living amoebae (fla) in soft contact lens wearers. in the present study an amoebic keratitis due to hartmannella has been recognized in a 22-year-old girl with a history of improper soft contact lens use. she had unilateral keratitis on her left eye. her clinical signs were eye pain, redness, blurr...