PURPOSE to describe the clinicopathologic features and treatment of a rare case of systemic paracoccidioidomycosis with choroidal and retinal involvement. DESIGN retrospective interventional case report. PARTICIPANT A 36-year-old young man with visual impairment in left eye with anterior uveitis and presence of whitish perimacular choroidal nodule, multiple underlying whitish spots and mid-...

An amoeba of the genus Naegleria causing fatal meningoencephalitis in a human subject has been investigated for its sensitivity to several drugs. Penicillin, sulphadiazine, chloramphenicol, oxytetracycline hydrochloride, streptomycin, methotrexate, emetine, quinine, and metronidazole had no effect on the organism in vitro at levels in excess of those likely to be attained therapeutically in the...

OBJECTIVE To compare topical diphenylhydantion (Phenytoin) with silver sulphadiazine/chlorhexidine (Silverex) in terms of rate of wound healing, analgesic and antibacterial properties in small to moderate-sized (< 30% TBSA) superficial dermal (second degree) burn wounds. DESIGN A prospective randomized controlled study. SETTING Surgical wards, Muhimbili National Hospital from July 2000 to F...

During the two years from March, 1950, to March, 1952, a working party established by the Antibiotics Clinical Trials (Non-tuberculous Conditions) Committee of the Medical Research Council investigated the clinical effects of chloramphenicol, aureomycin and sulphadiazine on infants suffering from gastro-enteritis (Medical Research Council, 1953). One of the 10 centres taking part was at Alder H...

Until 1960, 179 cases of infection with Nocardia asteroides had been described in the world literature. Seventeen cases in children were reported by 1963. The organism is a common saprophyte in nature with probably a world-wide distribution. Infection can be primary but is more common in patients with underlying malignancy, auto-immune disease or preceding tuberculosis. Sulphonamides, particula...

SYNOPSIS From 1966 to 1971, 298 cultures of meningococci from clinical material (cerebrospinal fluid or blood) were examined. Eighty-nine cultures were from the Manchester area and the remainder from other parts of England or Northern Ireland. Five per cent of strains were group A, 57% group B, and 31 % group C; 6% were untypable. Eighteen strains (6 %) had an MIC of 6 4 ,ug/ml or more of sodiu...

Trobicin (Actinospectacin) is a new antibiotic obtained from Streptomyces spectabilis developed by the Research Laboratories of Messrs. Upjohn. It is prepared as a white powder, 1 4-1 6 g. of which is dissolved in distilled water. It has been stated to have a wide range of antibacterial activity and has already been shown (Willcox, 1962) to be effective in cases of acute gonorrhoea in males whe...

recmr ln com^ined with sulphadiazine found the pati*ate ^3 Per cen^these s they noted as neurological sequelae 4 cases of brain damage giving rise to hydrocephalus, mental impairment and paralysis. These were all infants under 1 year. There were 4 other cases of deafness, partial or completeOne of us (Konar 1950) reported 3 cases of pneumococcal meningitis where neck rigidity and Kernig's sign ...