A complete approach for the search of top-quality six-bar linkages based on four-bar generating coupler curves with circular regions has been developed. The includes a robust algorithm to high-accuracy in and fitness function able evaluate quality resulting linkage. is used explore design space order optimal dwell identify types that provide best dwells according established criteria. Then, glo...

Presynaptic, electron-dense, cytoplasmic protrusions such as the T-bar (Drosophila) or ribbon (vertebrates) are believed to facilitate vesicle movement to the active zone (AZ) of synapses throughout the nervous system. The molecular composition of these structures including the T-bar and ribbon are largely unknown, as are the mechanisms that specify their synapse-specific assembly and distribut...

Females homozygous for the sex-linked dominant, Bar, occasionally give rise to wild-type reversions and to forms with more extreme eye reduction than Bar. This behavior was shown by Sturtevant' to result from unequal crossing-over. The Bar-reverted type was considered to be a deficiency for the Bar gene; while the extreme form, called Ultra-Bar or Double-Bar, was interpreted as a duplication fo...

In this paper, an auxiliary methodology called the creative mechanism design is introduced into the innovation of gripping devices for prosthetic hands. This methodology is a systematic approach based on modification of existing devices for the generation of all possible topological structures of mechanisms and mechanical devices. An existing gripping device (Teh Lin ATG-5F prosthetic hand) con...

1. Abstract This paper presents a simple approach to optimize the dimensions and the positions of 2D mechanisms for path or function-generator synthesis. The proposed method is particularly adapted to assembled mechanisms since time-varying dimensions always satisfy the assembly conditions which may represent a real difficulty when dealing with closed-loop mechanisms. The objective is to minimi...

This paper describes a case-study which illustrates the capabilities of a commercially available software package called SyMech, which runs within Pro/ENGINEER. The software allows a designer to synthesize arbitrarily complex planar mechanisms by sequentially specifying one of three basic mechanism design functions: position, path, or angle. Because the software runs directly within Pro/ENGINEE...