Marine macroalgae have an interesting profile of bioactive compounds and gained tremendous attention in cosmeceuticals with negligible toxicity effects (cytotoxicity, reproductive toxicity, genotoxicity, mutagenicity, carcinogenicity, etc.) on humans exhibit strong benefits for the skin. Among diversified compounds, phenolic are group phytochemicals found high amounts great structural diversity...

The increasing bacterial resistance to antibiotics is driving strong demand for new antimicrobial biomaterials. This work describes the fabrication of free-standing films exhibiting properties by combining, in same polypeptide chain, an elastin-like recombinamer comprising 200 repetitions pentamer VPAVG (A200) and 18-amino-acid truncated variant peptide BMAP-28, termed BMAP-18. fusion protein B...

background: bleomycin (blm) is an anti-cancer drug widely used in the treatment of cancer. blm causes several side effects related to dna and cellular damage. the aim of this study was investigated the effects of tea polyphenol epicatechin on anti-proliferative effects induced by bleomycin in human normal skin and human ovarian cancer cells.materials and methods: human ovarian cancer cell (skov...

in this study the role of glutathione (gsh) in sulfur mustard -induced oxidative stress and cytotoxicity, in human skin fibroblast cell line (hf2ff) was evaluated. sulfur mustard-induced superoxide radical and hydrogen peroxide formation were evaluated by determination of superoxide dismutase and catalase activity in cell lysate. the cytotoxicity of sulfur mustard was estimated by lactate dehyd...

Transcutaneous delivery of vaccines to specific skin dendritic cells (DC) subsets is foreseen as a promising strategy to induce strong and specific types of immune responses such as tolerance, cytotoxicity or humoral immunity. Because of striking histological similarities between human and pig skin, pig is recognized as the most suitable model to study the cutaneous delivery of medicine. Theref...

Purpose: The purpose of this study is to evaluate the skin wrinkle improvement effect a mixture Bletilla striata Reichenbach fil., Ampelopsis japonica, Angelica dahurica, Atractylodes Ligusticum sinense Oliv, officinale, and gigas (BAA).Methods: In study, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity evaluation, SOD (s...

Purpose: This study aimed to extract phyto DNA from the adventitious root of Aloe vera and confirm its role in improving regenerating skin antiaging properties caused by blue light.Methods: Phyto was extracted a complex containing polylysine Poly (amidoamine) made. The antioxidant activity confirmed using DPPH method. MTT test performed on fibroblasts. expression SOD1, FLG, LOR, COL1A1, MMP1 me...

in the recent years, the role of lox enzymes in the cause of neoplastic diseases such as colorectal, skin, pancreatic and renal cancers has been confirmed. a new series of 1,3,4-thiadiazole derivatives bearing 2-pyridyl moiety was synthesized and their cytotoxicity was assessed using mtt protocol. enzyme inhibitory activity of prepared compounds was also tested against 15-lipoxygenase-1 as nove...