The need for a long-term sustaining of optimal concentrations applied pesticides in the soil agriculture resulted development systems controlled release active substances. Such are based on use eco-friendly carrier materials that harmless to plants, humans and environment. Inorganic substances (e.g., clays or alike substances), biodegradable polymers natural synthetic origin, blends such their ...

Polyhexanide (polyhexamethylene biguanide) (PHMB) is a polymeric substance that broadly used as disinfectant and antiseptic. It was shown to be suitable for clinical use in critically colonized or infected acute chronic wounds since it exhibits broad antimicrobial spectrum combined with good cell tissue tolerability low risk of contact sensitization. Furthermore wound healing promoting effect r...

Synaptic transmission consists of fast and slow components of neurotransmitter release. Here we show that these components are mediated by distinct exocytic proteins. The Caenorhabditis elegans unc-13 gene is required for SV exocytosis, and encodes long and short isoforms (UNC-13L and S). Fast release was mediated by UNC-13L, whereas slow release required both UNC-13 proteins and was inhibited ...