Circadian clocks generate rhythms in molecular, cellular, physiological, and behavioral processes. Recent studies suggest that disruption of the clock mechanism accelerates organismal senescence and age-related pathologies in mammals. Impaired circadian rhythms are observed in many neurological diseases; however, it is not clear whether loss of rhythms is the cause or result of neurodegeneratio...

Title of dissertation: Real Time Terminal Area Trajectory Planning For Runway Independent Aircraft Min Xue, Doctor of Philosophy 2006 Dissertation directed by: Assistant Professor Ella M. Atkins Department of Aerospace Engineering The increasing demand for commercial air transportation results in delays due to traffic queues that form bottlenecks along final approach and departure corridors. In...

BACKGROUND Nerve injury-induced neuropathic pain is a major health problem worldwide. Notch signaling is a highly conserved pathway in evolution, which has an important role in synaptic plasticity and inflammation in central nervous system. The present study was designed to investigate the potential role of notch signaling in the development of neuropathic pain. METHODS The neuropathic pain w...

Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the body. It has been suggested that such side bias results from cortical function lateralization. It is not known, however, if other pain-associate...

Methods: A group of patients who had cervical or lumbar surgery with preoperative discrepancies between presenting exam and radiological imagery underwent selective nerve root injections prior to surgery. Strict criteria were adhered to in performing the SNIs, including use of fluoroscopy with contrast, nerve stimulation, concordance of stimulation and limited volume of local anesthetic. The SN...

The loss of autonomy at advanced ages is not only associated with ageing, but also with the characteristics of the physical and social environment. Recent investigations have shown that social networks, social engagement and participation act like predictors of disability among the elderly. The aim of this study is to determine whether social networks are related to the development and progress...

a r t i c l e i n f o Keywords: Signal-to-noise index (SNI) Charcoal analysis Fire history Lake sediment Paleoecology Charcoal peaks in lake-sediment records are commonly used to reconstruct fire histories spanning thousands of years, but quantitative methods for evaluating the suitability of records for peak detection are largely lacking. We present a signal-to-noise index (SNI) that quantifie...

Eavesdropping is becoming rampant on the Internet We as CERT IT have recorded a great number of sni ng attacks in the Italian community In fact sni ng is the most popular hacker s attack technique all over the Internet This paper presents a secure telnet implementation which has been designed by the Italian CERT to make eavesdropping ine ective to remote terminal sessions It is not to be consid...

In this study, we aim to determine the in vivo effect of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs) on neuropathic pain, using three, principal peripheral neuropathic pain models. Four weeks after hUCB-MSC transplantation, we observed significant antinociceptive effect in hUCB-MSC-transplanted rats compared to that in the vehicle-treated control. Spinal cord cells pos...