In this video Q & A, we talk to Ian Gilmore about the global burden of alcohol in terms of its scale, and its consequences in relation to non-communicable diseases and other illnesses. Sir Gilmore additionally discusses how the problem is being addressed, reviews the outcomes of recent initiatives and describes the challenge and future directions.

synthesis of some new monocyclic β-lactams containing a quaternary carbon center via a [2+2]cycloaddition reaction is described. the reaction of achiral diphenyl ketene with chiral aldimines derivedfrom chiral 2, 3, 4, 6-tetra-o-acetyl-β-d-galactopyranosylamine, 2, 3, 4, 6-tetra-o-acetyl-β-dglucopyranosylamine and different benzaldehydes resulted in the formation of β-lactams as singlediastereo...

The monolignols glucosides pglucocoumaryl alcohol, coniferin and syringin, have been found in cambial sap of gymnospermous trees (Freudenberg and Harkin 1963) and some species of angiospermous trees (Terazawa et al. 1984). Coniferin has been shown to bean effective precursor of lignin biosynthesis in pine (Freudenberg et al. 1955). When three kinds of monolignols glucosides labeled with C or H ...

The P atom in the title compound, C15H18NO3P, is in a distorted tetra-hedral P(O)(O)2N environment; the bond angles at P are in the range 98.16 (6)-115.82 (6)°. In the crystal, adjacent mol-ecules are linked via N-H⋯O=P hydrogen bonds into a chain running parallel to the b axis. The methyl groups are disordered over two sets of sites in a 0.677 (14):0.323 (14) ratio. The crystal studied was a n...

A family of virtually isostructural tetra-capped ε-Keggin-type polyoxomolybdate(V) cluster compounds, [Mo12(V)O28(μ(2)–OH)10(μ(3)–OH)2{M(II)(H2O)3}4]·nH2O ({M4(II)Mo12(V)}, M = Ni, Co), exhibits magnetic-field-dependent optical response in their electronic absorption spectra in the 0–33 T range. On the basis of Effective Hamiltonian Crystal Field calculations, we find that the observed field-in...

The title compound {systematic name: 2,2',2'',2'''-[3,7,11,15-tetra-aza-1(1,4),5(1,3),9(1,4),13(1,3)-tetra-benzena-cyclo-hexadeca-phane-3,7,11,15-tetra-yltetra-methyl-ene]tetra-benzonitrile}, C(64)H(56)N(8), is a centrosymmetric macrocycle that is consolidated into the crystal structure by C-H⋯π inter-actions.

TErrestrial Trunked Radio (TETRA) offers capabilities equivalent to the second generation of mobile phones with voice and limited data capabilities. TETRA needs to evolve to satisfy increasing user demand for new services and facilities as well as gleaning the benefits of new technology. An initial enhancement (TETRA Enhanced Data Service, TEDS) has been agreed. The enhanced TETRA services allo...

BACKGROUND The National Toxicology Program (NTP) performed short-term toxicity studies of tetra- and pentavalent vanadium compounds, vanadyl sulfate and sodium metavanadate, respectively. Due to widespread human exposure and a lack of chronic toxicity data, there is concern for human health following oral exposure to soluble vanadium compounds. OBJECTIVES To compare the potency and toxicologi...

Abstract This paper is devoted to the study of exclusive charm and bottom bound states which are suitable, at least partially, for a non-relativistic description. Starting from simple choice quarkonia tetra-quark wave functions we their production cross sections, total widths more interesting decay properties. In particular, compute sections ground state scalar getting results compatible with v...

Myxinol tetra-acetate was examined by both nuclear-magnetic-resonance and mass-spectral techniques. The results are compared with corresponding data for 5alpha-ranol tetra-acetate and 5alpha-cyprinol tetra-acetate. The structure deduced for myxinol tetra-acetate, 3beta,7alpha,16alpha,27-tetrahydroxy-5beta-cholestane, is in agreement with that simultaneously arrived at by Haslewood (1966).