Soft tissue sarcomas (STS) are a group of rare and heterogeneous cancers. While large-scale genomic epigenomic profiling STS have been undertaken, proteomic analysis has thus far limited. Here we utilise sequential window acquisition all theoretical fragment ion spectra mass spectrometry (SWATH-MS) for formalin fixed paraffin embedded (FFPE) specimens from cohort patients ( n = 36) across four ...

The development of a new soft tissue lesion in an otherwise healthy child, adolescent, or young adult can present many challenges for pediatric or medical oncology teams. Although uncommon, the diagnosis of a soft tissue malignancy should always be considered in the differential diagnosis of persistent pain, even if no mass is palpable. The definitive diagnosis and treatment of a soft tissue ma...

we present a case of allergic fungal sinusitis (afb) in a 20-year old man with few months' history of bilateral nasal obstruction and discharge with unilateral proptosis that underwent maxillary antrostomy due to the mass in paranasal sinuses. histological examination of tissue showed branching fungal hyphae interspersed with allergic mucin without fungal invasion to soft tissue. the patient re...

The present study aimed to investigate the imaging characteristics of primary malignant bone tumors in children. The imaging results of 34 children with primary malignant bone tumors confirmed by histopathological diagnosis between March 2008 and January 2014 were retrospectively analyzed. In total, 25 patients had osteosarcoma, with radiography and computed tomography (CT) showing osteolytic b...

A 44-year-old female with known primary myelofibrosis presented with shortness of breath. High Resolution Computed Tomography thorax revealed large heterogeneously enhancing extraparenchymal soft tissue density mass involving bilateral lung fields. F-18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography revealed mildly FDG avid soft tissue density mass with specks of calc...