We examined the tonal alignment and scaling patterns of the start and end points of the French late rise, using a rate manipulation paradigm. Our findings call into question aspects of the segmental anchoring hypothesis: the low starting point of the late rise was not stably anchored to a segmental landmark, and for some speakers, F 0 excursion size varied across rates. The position of the peak...

A broad diversity of biological organisms and systems interact with soil in ways that facilitate their growth survival. These interactions are made possible by strategies enable to accomplish functions can be analogous those required geotechnical engineering systems. Examples include anchorage soft weak ground, penetration into hard stiff subsurface materials movement loose sand. Since the have...

The aim of this trial was to evaluate and compare perceived pain, discomfort, and jaw function impairment between orthodontic treatments combined with skeletal anchorage and treatment using conventional anchorage with headgear or transpalatal bar. A total of 120 adolescent patients in order to start orthodontic treatment were consecutively recruited and randomized into three groups with differe...

Transforming growth factor-beta (TGF-beta) was originally identified, characterized, and named on the basis of its ability to induce anchorage-independent growth (phenotypic transformation). This effect has received little attention in recent years, probably because the induction of anchorage-independent growth by TGF-beta has been observed only in a few cell lines, of which NRK fibroblasts are...

Anchorage-independent growth is a hallmark of tumor cells. We compared gene expression profiles of anchored and nonanchored human mammary carcinoma cells to study this phenomenon. In this study, we show that anchorage had striking effects on cell growth and morphology but altered transcript levels from a limited number of genes. Only about 1% of mRNA transcripts detected in these cells was alte...

The stability of the anchorage unit plays a very important role in orthodontic control. Controlled orthodontic movements such as retraction and/or protraction of teeth and intrusion of overerupted teeth are very difficult to achieve without patient cooperation and without causing undesirable reciprocal movement in the anchorage unit. The article describes characteristics, surgical procedure, an...

A-kinase can inhibit RhoA activation through phosphorylating ser188 of RhoA. AKAP is a novel protein that can target PKA to different subcellular compartment. Evidence has been presented that PKA anchorage by AKAP is important for the kinase to exert its function. This study analyzed the role of PKA anchorage in PKA-induced antagonism against RhoA activity and function. The cells transfected wi...

INTRODUCTION This study was conducted to determine the efficiency of mini-implants as intraoral anchorage units for en-masse retraction of the 6 maxillary anterior teeth when the first premolars are extracted compared with conventional methods of anchorage reinforcement. METHODS Thirty patients requiring high anchorage after extraction of the maxillary first premolars were selected for this s...