background and objectives: the etiology, pathophysiology, nomenclature and clinical manifes-tation of solitary rectal ulcer syndrome (srus) is poorly understood. aim: to examine the pathology of mucosal changes and clinical features of this syndrome. materials and methods: the mucosal biopsies of 19 patients with clinical evidence of solitary rectal ulcer as been reviewed in accordance with the...

OBJECTIVE To evaluate, in a prospective study, the clinical outcome of orthotopic neobladder reconstruction after radical cystectomy in patients with a solitary functioning kidney at the time of surgery. PATIENTS AND METHODS This study included a total of 28 patients (25 males and three females) with muscle invasive bladder cancer and a solitary functioning kidney at the time of surgery who u...

PURPOSE We report our experience with patients with imperative indications for endoscopic treatment for upper tract transitional cell carcinoma. MATERIALS AND METHODS Between 1983 and 2004 we identified 37 patients with a solitary kidney, bilateral disease or preoperative creatinine greater than 2.0 mg/dl who underwent endoscopic treatment for localized upper tract transitional cell carcinoma...

BACKGROUND To present our experience with simultaneous combined minimally invasive percutaneous nephrolithotomy (MPCNL) and retrograde intrarenal surgery (RIRS) to manage patients with staghorn calculi in solitary kidney, and evaluate the safety, efficiency and feasibility of this approach. METHODOLOGY/PRINCIPAL FINDINGS The study included 20 patients with staghorn calculi in solitary kidney....

In male adolescent rats kidney mass attained maximum terminal value already at week 1 after streptozotocin treatment, and this value did not change over the next two weeks. At week 1 the kidney size of diabetic rats was greater than that of untreated controls, whereas at week 3 renal mass was the same in both groups. In adult rats with final body and kidney mass streptozotocin treatment failed ...

Introduction Angiomyolipoma (hamartoma) of the kidney is a rare finding. Hajdu and Foote (1969) recorded an incidence of 0.31% in 8501 post-mortem cases. McCullough, Scott and Seybold (1971), Becker et al. (1973), Honey and Honey (1977) consider that 50-80% of renal hamartomas appear in patients with tuberose sclerosis. Angiomyolipomas without tuberose sclerosis are usually solitary and unilate...

A 28 year old man presented with haematuria and renal failure. Renal arteriography revealed bleeding into the pelvis of a solitary right kidney from a hilar artery. Multiple aneurysms were noted in the splenic artery. The spleen subsequently ruptured spontaneously and was removed at laparotomy together with the right kidney. Histological examination of the spleen and kidney revealed an acute ne...

A 3 years old boy with a history of surgery for orchidopexy was admitted to our hospital with fever and abdominal pain. Clinical examination and laboratory investigations revealed urinary tract infection with renal involvement. Ultrasonography demonstrated a solitary left kidney and raised the suspicion of a fusion anomaly. Voiding cystography disclosed grade III vesicoureteral reflux and tec...

BACKGROUND Patients with unilateral MultiCystic Kidney Dysplasia (MCKD) or unilateral renal agenesis (URA) have a congenital solitary functioning kidney (CSFK) that is compensatory enlarged. The question whether this enlargement is due to increased nephron numbers and/or to nephron hypertrophy is unresolved. This question is of utmost clinical importance, since hypertrophy is associated with a ...