We have achieved highly localized control of pattern formation in two-dimensional nanoparticle assemblies by direct modification of solvent dewetting dynamics. A striking dependence of nanoparticle organization on the size of atomic force microscope-generated surface heterogeneities is observed and reproduced in numerical simulations. Nanoscale features induce a rupture of the solvent-nanoparti...

      The first aim of the present investigation was to prepare solid dispersions to improve the dissolution properties of oxcarbazepine and quetiapine using PEG 6000 as a carrier with the help of two methods of preparations viz. spray drying and modified solvent method, and to compare the two methods. The second objective was to apply the modified solvent method for preparation of sustained re...

We have created nanospirals by self-assembly during droplet evaporation. The nanospirals, 60-70 nm in diameter, formed when solvent mixtures of methanol and m-cresol were used. In contrast, spin coating using only methanol as the solvent produced epitaxial films of stripe nanopatterns and using only m-cresol disordered structure. Due to the disparity in vapor pressure between the two solvents, ...

0308-8146/$ see front matter Published by Elsevier doi:10.1016/j.foodchem.2008.08.046 * Corresponding author. Tel.: +510 559 5898; fax: + E-mail address: [email protected] (A.P. A preparative method for decigram-scale polishing of limonin glucoside (1) with regard to removing traces of limonin (2), the main bitter principle in Citrus, is reported. During the method development and up-s...

Solvent extraction/evaporation, solvent diffusion/evaporation or any modification in the basic principle of the emulsification technique produces the drug loaded sustained release micro or nanoparticles of desired properties. For understanding the basic principles of these techniques, it is essential for the development of desired objectives. Emulsification is the only step where we can disrupt...

Abstract: Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve solubility slowly dissolving drugs. A variety pharmaceutically compatible additives using different emerging technology used for preparing SDs. Multiple approaches were designed prepare SDs by such as kneading, co-milling, fusion, solvent evaporation various solvent-associated methods. The selection a...

A mucoadhesive drug delivery system for local delivery of metronidazole through vaginal route was formulated. Films were prepared by solvent evaporation method using various compositions of Carbopol, hydroxypropylmethylcellulose, chitosan, Polyox and propylene glycol. The films were evaluated for their weight, thickness, surface pH, folding endurance, mechanical, drug content uniformity, in vit...