background: our study aimed at substantiating the recent claim of myo-cardial complications in severe malaria by experimentally inducing severe plasmodium falciparum infection in a humanized mouse model employed as human surrogate. methods: twenty five humanized mice were inoculated with standard in vitro cultured p. falciparum and blood extracts collected from the inner cardiac muscles of infe...

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maintenance treatment for patients with acute myeloid leukemia (aml) in remission has recently been controversially discussed and even abandoned by several groups. an analysis of 16 published multicenter trials, however, revealed the highest probabilities of relapse free survival (rfs) in the range of 35-42 % at 4-5 years only in patients assigned to maintenance treatment when adult age and int...

abstract introduction & objective: enuresis is defined as involuntary voiding. it is a socially disruptive and stressful condition which affects around 15% of five years old children and up to 1% of adults. aim the aim of this study was to assess the efficacy of desmopressin (nasal spray) and oxybutinin combination therapy in treatment of patients with primary nocturnal enuresis that were resis...

introduction: chemotherapy-induced oral mucositis (com) is a common, debilitating complication of cancer therapy. the aims of this study were to evaluate the effect of low level laser therapy (lllt) on prevention of com in patients with hematologic malignancies. methods: fifty-five patients hospitalized to undergo chemotherapy in imam hospital were included into the study. these patients were d...

introduction: the aim of this study was to determine the histologic effect of low level laser therapy (lllt) with or without the use of mineral trioxide aggregate (mta) on exposed pulp tissues of dogs. methods: twenty-five premolar teeth in three healthy mature dogs were randomly divided into five groups. in group 1, the pulp tissue was capped with mta. in groups 2 and 3, before capping with mt...

extensive job stress and workload are main causes of frustration and reduced efficiency among workers and despite negative effects of these factors on employees' performance, related studies in rehabilitation staff are limited. the aim of this study was to evaluate job stress, workload and their related factors in rehabilitation staff. in this cross-sectional study, 150 employees in three ...

abstract prostate cancer is one of the life threatening disorders of male. although, over the last two decades, a high rate of overdiagnosis, and overtreatment has lowered the incidence rate of prostate cancer, the treatment or prevention strategies are not enough to control the high rate of disease related mortality. current medical treatment approaches include surgery, radiation therapy, chem...

purpose: to investigate the effectiveness of metacognitive therapy in patients with major depressive disorder. the population of this study included all patients admitted to the army hospital no. 520 diagnosed with major depressive disorder from which 30 individuals were selected by using random sampling into experimental and control groups (n = 15 experimental and n = 15 control). materials an...