Targeted genetic studies can facilitate phenotypic analyses and provide important insights into development and other complex processes. The SWI2/SNF2 DNA-dependent ATPase Domino (Dom) of Drosophila melanogaster, a component of the Tip60 acetyltransferase complex, has been associated with a wide spectrum of cellular processes at multiple developmental stages. These include hematopoiesis, cell p...

In today’s web applications, JavaScript code interacts with the Document Object Model (DOM) at runtime. This runtime interaction between JavaScript and the DOM is errorprone and challenging to test. In order to unit test a JavaScript function that has read/write DOM operations, a DOM instance has to be provided as a test fixture. This DOM fixture needs to be in the exact structure expected by t...

An H-system is a system of first-order linear homogeneous recurrence equations for a single unknown function T , with coefficients which are polynomials with complex coefficients. We consider solutions of H-systems which are of the form T : dom(T ) → C where either dom(T ) = Z, or dom(T ) = Z \ S and S is the set of integer singularities of the system. It is shown that any natural number is the...

We aimed to investigate the application of combined mechanistic pharmacokinetic (PK) and pharmacodynamic (PD) modeling and simulation in predicting the domperidone (DOM) triggered pseudo-electrocardiogram modification in the presence of a CYP3A inhibitor, ketoconazole (KETO), using in vitro-in vivo extrapolation. In vitro metabolic and inhibitory data were incorporated into physiologically base...

This paper firstly presents a novel constraint-handling technique , called dynamicobjective method (DOM), based on the search mechanism of the particles of particle swarm optimization (PSO). DOM converts the constrained optimization problem into a bi-objective optimization problem, and then enables each particle to dynamically adjust its objectives according to its current position in the searc...

We propose and prove sound a novel, purely dynamic, flowsensitive monitor for securing information flow in an imperative language extended with DOM-like tree operations, that we call Core DOM. In Core DOM, as in the DOM API, tree nodes are treated as first-class values. We take advantage of this feature in order to implement an information flow control mechanism that is finer-grained than previ...

For simplicity, we adopt the following rules: X is a non empty set, S is a σ-field of subsets of X, M is a σ-measure on S, E is an element of S, F , G are sequences of partial functions from X into R, I is a sequence of extended reals, f , g are partial functions from X to R, s1, s2, s3 are sequences of extended reals, p is an extended real number, n, m are natural numbers, x is an element of X...

Aquacultures are of great economic importance worldwide but pollute pristine headwater streams, lakes, and estuaries. However, there are no in-depth studies of the consequences of aquacultures on dissolved organic matter (DOM) composition and structure. We performed a detailed molecular level characterization of aquaculture DOM quality and its bacterial degradation using four salmon aquaculture...

Iron that precipitates under aerobic conditions in natural aquatic systems scavenges dissolved organic matter (DOM) from solution. Subterranean estuaries (STEs) are of major importance for land-ocean biogeochemical fluxes. Their specific redox boundaries, coined the "iron curtain" due to the abundance of precipitated iron(III) (oxy)hydroxides, are hot spots for the removal and redissolution of ...

The notation and terminology used in this paper have been introduced in the following articles: [20], [9], [25], [7], [8], [4], [16], [24], [21], [19], [13], [18], [23], [1], [2], [10], [5], [17], [11], [3], [22], [14], [12], [6], [26], and [15]. We use the following convention: i, j, n denote natural numbers, f , g, h, k denote finite sequences of elements of R, and M , N denote non empty metr...