نتایج جستجو برای: spatial learning and memory
تعداد نتایج: 17015447 فیلتر نتایج به سال:
probiotics lactobacillus plantarum and bifidobacterium b94: cognitive function in demyelinated model
background: multiple sclerosis (ms) is a disease of the immune system that creates damage of learning and memory in that. using probiotic supplements is recommended for preventing ms disease and improving memory. this study aimed to investigate the effect of lactobacillus plantarum (lp) and bifidobacterium b94 (bb94), on acquisition phase of spatial memory in the local demyelination of rats` hi...
Introduction: Alzheimer’s disease is one of the most prevalent brain neurodegenerative diseases and the most common cognitive deficits are memory dysfunction and spatial perception impairment. Progesterone has a neorostroid action in hippocampal neurogenesis, synaptic stability and spatial learning and memory and has antioxidant effect. Since oxidative stress is involved in the pathogenes...
Background: Spinach (Spinacia oleracea L.) has antioxidant, antiinflammatory, antiapoptotic and neuroprotective properties. The aim of this study was to investigate the effect of spinach hydroalcoholic extract on chronic restraint stress-induced spatial learning and memory deficit and anxiety in adult male rats. Methods: 60 adult male Wistar rats were allocated to six groups: Control group, Sp...
Background: Numerous evidences indicate that various environmental stresses during pregnancy affect physiological behavior of the offspring. This experimental study was designed to investigate the effect of noise stress during prenatal period of rats on spatial learning and memory and plasma corticostrone level in postnatal life.Methods: Three groups of pregnant rats were given daily noise ...
Background: Testosterone and its metabolites have important roles in learning and memory. The current study has conducted to assess the effect of pre-training, post-training and pre-probe trial intrahippocampal CA1 administration of 3 alpha-anderostanediol (one of the metabolites of testosterone) and indomethacin (as 3 alpha-hydroxysteroid dehydrogenase enzyme blocker) on acquisition, consolida...
background: fetal alcohol syndrome is associated with numerous problems in the development and function of the brain. learning and memory deficits are among well known effects of prenatal exposure to alcohol. objective: this study aimed to examine the spatial working memory of 60-day old rats who were exposed to alcohol during their fetal life and to find the relation between the possible alcoh...
Introduction: A large body of evidence points to oxidative stress as prime candidate mediating the behavioral impairments and memory deficits in Alzheimer's disease (AD). It has been demonstrated that hyperoxia preconditioning activates complex endogenous neuroprotective mechanisms including an increase in capacity of antioxidant defence mechanisms. The aim of this study was to investigate the ...
objective(s) we determined the effect of a high fructose diet either alone or in combination with iranian shallot or garlic extract on cognitive functions, plasma lipid profile, and the intraperitoneal glucose tolerance test (ipgtt). materials and methods following induction of insulin resistance in fructose-fed rats (fru-fed), they were randomly assigned to three subgroups. the first subgroup ...
Background & Aim: Opiates addiction is a phenomenon with complex physiological and social causes and consequences. The exact mechanisms of development of dependency and relapse remain unclear. Among the several possible mechanisms, the role of learning and memory in opiate dependency and relapse has received considerable attention in recent years. Therefore, in the current study the effect ...
Introduction: Patients with epilepsy can have impaired cognitive abilities. Many factors contribute to this impairment, including the adverse effects of antiepileptic drugs like Gabapentin (GBP). Apart from anti-epilectic action, Gabapentin is used to relieve ethanol withdrawal syndrome. Because both GBP and ethanol act on GABA ergic system, the purpose of this study was to evaluate their effe...
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