In order to evaluate the effects of phenytoin on the reproductive system of rats in detail, 60 male rats were divided equally into 6 groups: 1-5 received 10 mg/kg/day phenytoin IP for 1,2,3,4 and 5 weeks, respectively. However, group 5 did not receive any phenytoin for the last 5th week. The control group (group 6) did not receive any treatment. The results revealed that phenytoin does not ...

Cytochrome P450 aromatase is the key enzyme in estrogen biosynthesis, encoded by CYP19 gene. Impairment of spermatogenesis associated with a decrease in sperm motility and inability to fertilize oocytes in mice due to the lacking of CYP19 was observed. However, it is little known about the CYP19 roles in boar spermatogenesis and fertility. Therefore, the aim of this research was to investigate ...

1st century A.D.: Celsius reported that swollen veins over the testis associated are with small testis. Mid-19th century: Inflammation of male and female reproductive organs was treated with ointments, douches and massages. 1881: Dr. Levy a German gynecologist performed a post coital test for an infertile couple and determined that the husband was sterile (no sperm on microscopic exam). Late 19...

Background: Formation of hydrogen peroxide derivativesdue to metabolic disturbances in the male diabetics can affect their fertility. The antioxidant property of sesame oil has been documented, previously. The primary aim of the present study was to find if sesame oil supplementation can reduces the impact of diabetes on sperm parameters in rat or not. Materials and Methods: Eighteen numbers of...

Background: para-nonylphenol (p-NP) is able to induce malformations in male reproductive system. Objective: The aim of this study was to investigate the preventing role of vitamin E (Vit.E) on sperm parameters and reproductive hormones in developing rats. Materials and Methods: Pregnant rats were divided into 4 groups: control, p-NP, Vit.E and p-NP+Vit.E. Treatments were performed on day 7 of g...

BACKGROUND The use of testicular sperm in assisted reproduction depends on the availability of sperm in wet preparations. It is not always possible to recover sperm from the testis, even with previous sperm-positive histopathological findings. The purpose of this study was to evaluate the sperm-negative wet preparation search results with flow cytometric ploidy analysis and histopathological ex...

Twenty-four Sprague-Dawley male rats (7-9 weeks old, 200-250 g) were divided into Nicotine (N) (0.5 mg/100 g body weight (BW), Nicotine Control (NC) (saline, 0.1 mL/100 g BW), Habbatus sauda oil (HS) (6.0  μ L/100 g BW), and Habbatus sauda Control (HSC) (corn oil, 0.1 mL/100 g BW) groups and treated for 100 days. Sperm parameters and seminiferous tubules measurements were evaluated. The N showe...

Glifosat bazlı formülasyonlar, dünyada en yaygın kullanılan herbisit tarım ilaçlarındandır. Bu çalışmada, su kaynaklı glifosatın erkek Nil Tilapyası (Oreochromis niloticus) testis, sperm kanalı, testiküler ve sağım yolu ile elde edilmiş spermatozoa örnekleri üzerine etkileri belirlenmiştir. amaçla, balıklar 14 gün boyunca 0, 5, 10, 20, 30 40 mg/L glifosat içeren deneme akvaryumlarında tutulmuşl...

Testis-specific proteins, synthesized during spermatogenesis and spermiogenesis, are necessary for spermatid differentiation and/or for mature sperm function during fertilization. However, majority of these genes have neither been identified nor fully characterized. Testis developmental related gene 1 (TDRG1), a newly identified human testis-specific gene, encodes a 100-amino-acid protein witho...

Galectin-3, a member of the beta-galactoside-binding protein family, has been implicated in mammalian sperm maturation. We examined galectin-3 expression in the testis and epididymis of sexually mature and immature bulls. Western blot analysis showed varying levels of galectin-3 in the bull testis and epididymis, and galectin-3 immunoreactivity was higher in the mature testis and epididymis tha...